Results 11 to 20 of about 663,827 (314)

Pancreas [PDF]

open access: yesAmerican Journal of Transplantation, 2016
Even though pancreas transplant numbers have steadily declined over the past decade, new listings increased in 2014 compared with the previous year, notably for pancreas transplant alone (PTA) and simultaneous pancreas‐kidney transplant.
R. Kandaswamy   +7 more
semanticscholar   +3 more sources

Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

open access: yesMolecular Cancer, 2018
Background Long non-coding RNAs (lncRNAs) play an important role in the development and progression of various tumors, including pancreatic cancer (PC). Recent studies have shown that lncRNAs can ‘act in cis’ to regulate the expression of its neighboring
Hao Hu   +14 more
doaj   +1 more source

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.

open access: yesPhysiological Research, 2001
Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The mechanism of their action in B cells of the pancreas has been intensively investigated and now is quite well understood.
T. Szkudelski
semanticscholar   +1 more source

Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas.

open access: yesGastroenterology, 2020
BACKGROUND AND AIMS Molecular evidence of cellular heterogeneity in the human exocrine pancreas has not been yet established, due to the local concentration and cascade of hydrolytic enzymes that can rapidly degrade cells and RNA upon pancreatic ...
L. Tosti   +16 more
semanticscholar   +1 more source

Evolution of Insulin Delivery Devices: From Syringes, Pens, and Pumps to DIY Artificial Pancreas

open access: yesDiabetes Therapy, 2020
The year 2021 will mark 100 years since the discovery of insulin. Insulin, the first medication to be discovered for diabetes, is still the safest and most potent glucose-lowering therapy.
J. Kesavadev   +3 more
semanticscholar   +1 more source

CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

open access: yesMolecular Cancer, 2022
Background circular RNAs (circRNAs) have been reported to play crucial roles in the biology of different cancers. However, little is known about the function of circSTX6 (hsa_circ_0007905) in pancreatic ductal adenocarcinoma (PDAC).
Lingdong Meng   +13 more
doaj   +1 more source

Identification of genomic instability related lncRNA signature with prognostic value and its role in cancer immunotherapy in pancreatic cancer

open access: yesFrontiers in Genetics, 2022
Background: Increasing evidence suggested the critical roles of lncRNAs in the maintenance of genomic stability. However, the identification of genomic instability-related lncRNA signature (GILncSig) and its role in pancreatic cancer (PC) remains largely
Xiaole Zhu   +11 more
doaj   +1 more source

A Single-Cell Transcriptome Atlas of the Human Pancreas

open access: yesCell Systems, 2016
Summary To understand organ function, it is important to have an inventory of its cell types and of their corresponding marker genes. This is a particularly challenging task for human tissues like the pancreas, because reliable markers are limited. Hence,
Mauro J. Muraro   +10 more
semanticscholar   +1 more source

Laparoscopic treatment for an intrapancreatic accessory spleen: A case report

open access: yesFrontiers in Oncology, 2022
Malignant pancreatic tumors have early metastasis, aggressive behavior and poor prognosis. Surgeons often need to judge whether a patient needs prompt surgery when a pancreatic lesion is found.
Yihan Zhang   +17 more
doaj   +1 more source

DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation [PDF]

open access: yesInternational Conference on Medical Image Computing and Computer-Assisted Intervention, 2015
Automatic organ segmentation is an important yet challenging problem for medical image analysis. The pancreas is an abdominal organ with very high anatomical variability.
H. Roth   +6 more
semanticscholar   +1 more source

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