Results 261 to 270 of about 2,890,603 (393)

Clinical characteristics and outcomes of diabetes‐related ketoacidosis (DKA) in sodium‐glucose co‐transporter‐2 inhibitor (SGLT2i) users with type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Sodium‐glucose co‐transporter‐2 inhibitors (SGLT2i) offer significant cardiorenal benefits for people with type 2 diabetes (PwT2D). However, concerns remain regarding their association with diabetes‐related ketoacidosis (DKA). (1) To compare demographics, precipitating factors, biochemical features, management, and outcomes of acute DKA ...
Angelica Sharma   +11 more
wiley   +1 more source

Early insulin degludec with continuous intravenous insulin infusion in the management of diabetic ketoacidosis: A randomized controlled trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To determine the effectiveness and safety of early combination therapy with insulin degludec and intravenous insulin infusion (IVII) compared with IVII alone in diabetic ketoacidosis (DKA) management. Materials and methods This prospective, open‐label, randomised controlled trial included 80 adults (≥18 years) with DKA.
Kitti Thammakosol   +3 more
wiley   +1 more source

Tandem combination of ASCT and CAR T‐cell therapy in highly refractory CNS lymphomas

open access: yes
British Journal of Haematology, EarlyView.
Lydia Montes   +19 more
wiley   +1 more source

Declining incidence of hypoglycaemia in diabetes secondary to chronic pancreatitis: A nationwide cohort study from 2003 to 2022

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Population‐based studies have consistently shown that individuals with diabetes secondary to chronic pancreatitis (pancreatic diabetes) have a high risk of hypoglycaemia. We aimed to investigate whether this risk has declined over recent years following the introduction of modern glucose‐lowering medications. Materials and Methods In this
Line Davidsen   +5 more
wiley   +1 more source

Efficacy and safety in tirzepatide‐treated Korean adults with type 2 diabetes—A post hoc analysis of SURPASS‐AP‐combo and SURPASS‐3

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This post hoc analysis assessed the efficacy and safety data in tirzepatide‐treated Korean patients with type 2 diabetes (T2D). Materials and Methods Data specifically from Korean patients treated with tirzepatide 5, 10, or 15 mg in the multicentre, randomised, open‐label, parallel‐group, phase 3 trials SURPASS‐AP‐Combo and SURPASS‐3 were
Byung Wan Lee   +11 more
wiley   +1 more source

Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Retatrutide, a novel synthetic molecule, is a triple agonist activating the glucose‐dependent insulinotropic polypeptide, glucagon‐like peptide‐1 and glucagon receptors. The TRIUMPH clinical development program evaluates its safety and efficacy concurrently for the treatment of obesity and two related complications—obstructive sleep apnea
Kathryn Giblin   +8 more
wiley   +1 more source

Impact of acute pancreatitis on the outcomes of cholecystectomy. An observational multicenter retrospective study. [PDF]

open access: yesLangenbecks Arch Surg
Nawacki Ł   +15 more
europepmc   +1 more source

Incretin system and glucagon secretion in patients with chronic pancreatitis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Diabetes of the exocrine pancreas (DEP) showed unclear incretin and glucagon dynamics. This cross‐sectional study compared 32 patients with chronic pancreatitis (wCP) and 60 without (w/oCP). Subjects wCP had worse beta‐cell function and lower incretin effect.
Gea Ciccarelli   +16 more
wiley   +1 more source

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