Results 101 to 110 of about 985,459 (353)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Agreement between commercial assays for haptoglobin and serum amyloid A in goats

Acta Veterinaria Scandinavica, 2017
Haptoglobin (Hp) and serum amyloid A (SAA) are considered as the major acute phase proteins (APPs) in goats. These APPs have been investigated in several studies during the last decade.
Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Daria Reczyńska, Emilia Bagnicka, Jarosław Kaba   +8 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 Infection

PLoS Pathogens, 2010
The earliest immune responses activated in acute human immunodeficiency virus type 1 infection (AHI) exert a critical influence on subsequent virus spread or containment.
H. Kramer, Kerry J. Lavender, L. Qin, Andrea R. Stacey, Michael K P Liu, K. di Gleria, A. Simmons, N. Gasper-Smith, B. Haynes, A. McMichael, P. Borrow, B. Kessler   +11 more
semanticscholar   +1 more source

Acute phase proteins in psoriasis

Collegium antropologicum, 2009
Psoriasis is a chronic, relapsing, inflammatory and hyperproliferative skin disorder. The levels of acute phase proteins are suggested to be elevated in those patients with acute disease. The expression of selected acute phase proteins as the parameters of humoral immunity has been analyzed in 70 patients with acute psoriasis and 40 healthy controls ...
Kostović, Krešimir, Šitum, Mirna, Batinac, Tanja, Biljan, Darko, Matišić, Danica   +4 more
openaire   +2 more sources

Acute Phase Proteins as Cancer Biomarkers [PDF]

, 2011
Interactions between tumor cells and the host microenvironment have been shown to play a significant role in the initiation, progression, and invasiveness of human cancer. The complex changes in the tumor microenvironment have been shown to modulate the activation of the different arms of the host immune system including the acute phase response. Acute
Linda H. Malkas, W. Shannon Orr, Robert J. Hickey, John A. Sandoval   +3 more
openaire   +3 more sources

Acute phase proteins, saliva and education in laboratory science: an update and some reflections

BMC Veterinary Research, 2019
This manuscript provides updated knowledge and some ideas and reflections about three areas which are currently of interest in the field of the animal laboratory science.
José J. Cerón
doaj   +1 more source

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. [PDF]

, 1987
Jack Gauldie, Carl D. Richards, D.C. Harnish, Peter M. Lansdorp, H Baumann   +4 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Characterization of Acute-Phase Proteins (Apps) [PDF]

, 2012
Upon Injury, a complex biological response of tissues is initiated to protect the organism and remove the injurious stimuli then trigger the healing process. Inflammation is a part of this complex response. The local response to tissue injury or infection is acute inflammation. Without inflammation, wounds and infections would never heal. This response
Ying Chu Lee, Sin Tak Chu
openaire   +3 more sources