Results 171 to 180 of about 593,677 (304)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Complement regulation in innate immunity and the acute-phase response: inhibition of mannan-binding lectin-initiated complement cytolysis by C-reactive protein (CRP) [PDF]

, 1998
Chusana Suankratay, Carolyn Mold, Y Zhang, Lawrence A. Potempa, Thomas F. Lint, H Gewurz   +5 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Induction of endogenous retroviral gene product (SU) as an acute-phase protein by IL-6 in murine hepatocytes

, 1992
Y Itoh, Naoki Maruyama, Masanori Kitamura, Takuji Shirasawa, Kazuhiro Shigemoto, Takayoshi Koike   +5 more
openalex   +2 more sources

Cutting Edge: The Induction of Acute Phase Proteins by Lipopolysaccharide Uses a Novel Pathway That Is CD14-Independent [PDF]

, 1998
Alain Haziot, Xing Y. Lin, Fan Zhang, Sanna M. Goyert   +3 more
openalex   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

SERUM ACUTE PHASE PROTEINS AFTER ORTHOTOPIC LIVER TRANSPLANTATION

, 1990
A. M. Burns, M. P. Shelly, Sarah K. Walker, G.R. Park   +3 more
openalex   +1 more source

Acute phase proteins and recombinant IL-2 therapy: prediction of response and survival in patients with colorectal cancer [PDF]

, 1995
William G. Simpson, Steven D. Heys, P. H. Whiting, Oleg Eremin, J. Broom   +4 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Circulating levels of IL-11 and leukaemia inhibitory factor (LIF) do not significantly participate in the production of acute-phase proteins by the liver [PDF]

, 1996
Cem Gabay, Madeleine Ngandeu Singwé, Bernard Genin, Oliver Meyer, Gilles Mentha, Claude Le Coultre, T. L. Vischer, P-A Guerne   +7 more
openalex   +1 more source