Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
The effect of Lupinus angustifolius supplementation in laying hens on the liver proteome profiles and the concentration of acute phase proteins in serum and liver. [PDF]
Grabowski S+5 more
europepmc +1 more source
Study of the Genetic Expression of Antiretroviral Restriction Factors and Acute Phase Proteins in Cattle Infected with Bovine Leukemia Virus. [PDF]
González-Méndez AS+3 more
europepmc +1 more source
The Acute Phase Response of Adult Rats is Altered by in Utero Exposure to Maternal Low Protein Diets
Simon C. Langley‐Evans+3 more
openalex +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
[18F]Florbetaben PET-CT confirms AL amyloidosis in a patient with Waldenström’s Macroglobulinemia
Thomas A. Fox+5 more
doaj +1 more source
Acute phase proteins patterns as biomarkers in bacterial infection: Recent insights. [PDF]
Ali AA, Darwish WS.
europepmc +1 more source
Serial evaluation of thoracic radiographs and acute phase proteins in dogs with pneumonia. [PDF]
Menard J+5 more
europepmc +1 more source
Circulating levels of IL-11 and leukaemia inhibitory factor (LIF) do not significantly participate in the production of acute-phase proteins by the liver [PDF]
Cem Gabay+7 more
openalex +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source