Results 171 to 180 of about 148,904 (257)

Oxidative Fast Pyrolysis Enabling Autothermal Production of Porous Functionalized Biochar and Anhydrosugar/Phenol‐Rich Bio‐Oil From Biomass

open access: yesCarbon Energy, EarlyView.
Oxidative fast pyrolysis of biomass enables autothermal production of value‐added products. ABSTRACT Oxidative fast pyrolysis can potentially overcome the heat‐supply bottleneck of conventional fast pyrolysis by enabling autothermal operation while also tailoring product quality through controlled oxygen addition.
Bin Li   +15 more
wiley   +1 more source

Warm season hourly temperature and psychiatric emergencies: A case-crossover study of a vulnerable population in Boston, 2005-2019. [PDF]

open access: yesEnviron Epidemiol
Burrows K   +9 more
europepmc   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le   +8 more
wiley   +1 more source

Municipal intermediate care services in Denmark and Norway: a cross-country comparative analysis. [PDF]

open access: yesScand J Prim Health Care
Udesen SEJ   +4 more
europepmc   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang   +2 more
wiley   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

open access: yesDrug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe   +5 more
wiley   +1 more source

Nature-based interventions in psychiatric inpatient settings. [PDF]

open access: yesFront Psychiatry
Amann J   +4 more
europepmc   +1 more source

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