Advanced Science, EarlyView.This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao +13 more
wiley +1 more source
Comparison Between Antigen and Allelic HLA Mismatches, and the Risk of Acute Rejection in Kidney Transplant Recipients. [PDF]
HLAGately R +13 more
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Sustained Molecular Allograft Injury After Episodes of Acute Rejection and Organizing Pneumonia Increases the Risk of Lung Allograft Failure. [PDF]
Transplant DirectKeller MB +13 more
europepmc +1 more source
THE RELATIONSHIP OF GLUCOSE DISAPPEARANCE RATE (kG) TO ACUTE PANCREAS ALLOGRAFT REJECTION
, 1994 Debra S. Elmer +4 more
openalex +1 more source
Inflammatory cells and activation markers in BAL during acute rejection and infection in lung transplant recipients: a prospective, longitudinal study [PDF]
, 1997 G.C. Riise +6 more
openalex +1 more source
Confocal Absorbance‐Activated Droplet Sorting (cAADS) for Enzyme Engineering
Advanced Science, EarlyView.A custom confocal absorbance‐activated droplet sorting (cAADS) platform is presented, which confines illumination and detection to a small area on the “droplet plane”, enabling enhanced sensitivity at ultrahigh throughput. System performances and versatility are demonstrated by screening Bilirubin Oxidase encapsulated in 10 pL droplets at 5.4 kHz ...
Abdi Mirgissa Kaba +5 more
wiley +1 more source
Advanced Science, EarlyView.Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan +10 more
wiley +1 more source
Comparison of domino transplantation with Two-Way Paired Exchange and normal transplantation: acute rejection, surgical complications, and 5-year survival outcomes. [PDF]
Langenbecks Arch SurgHuseynov A, Cicek SNK.
europepmc +1 more source