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Advances in Immunosuppressive Agents Based on Signal Pathway [PDF]

open access: yesFrontiers in Pharmacology, 2022
Immune abnormality involves in various diseases, such as infection, allergic diseases, autoimmune diseases, as well as transplantation. Several signal pathways have been demonstrated to play a central role in the immune response, including JAK/STAT, NF ...
Zhiqing Xu, Zhiqing Xu, Ming Chu
doaj   +4 more sources

Failure of primary immunosuppressive agents in uveitis [PDF]

open access: yesIndian Journal of Ophthalmology
Purpose: This retrospective study aimed to evaluate the effectiveness of various immunomodulatory therapy (IMT) regimens in managing non-infectious uveitis (NIU) and to identify optimal treatment strategies for refractory cases.
Ankush Kawali   +4 more
doaj   +2 more sources

Efficacy of Tripterygium glycosides in immune-mediated kidney diseases as a immunomodulation drug in combination with conventional immunosuppressive agents: a systematic review and meta-analysis of randomized controlled trials [PDF]

open access: yesFrontiers in Pharmacology
BackgroundImmune-mediated kidney diseases involve the immune system attacking the kidneys, resulting in damage and dysfunction. Tripterygium glycosides (TG) are known for their strong immunosuppressive and anti-inflammatory effects and are commonly used ...
Yaotan Li   +14 more
doaj   +2 more sources

Case report: Managing pemphigus foliaceus using apremilast without systemic glucocorticosteroids or immunosuppressive agents [PDF]

open access: yesFrontiers in Immunology
Pemphigus foliaceus (PF) is a superficial form of pemphigus. Treatment options for PF resemble pemphigus vulgaris, including glucocorticosteroids, immunosuppressive agents and rituximab et al.
Quanhong Zhang   +8 more
doaj   +2 more sources

Actinomycosis in a Mucosal Lesion on a Created Perioral Dimple: A Case Report [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2017
Facial dimple creation is a simple surgical procedure. Nonetheless, several complications can occur. Actinomycosis is a rare chronic granulomatous infection caused by Actinomyces species.
Ui Geon Kim   +3 more
doaj   +1 more source

Immunosuppressive therapy in non-infections uveitis and retinovasculitis

open access: yesOftalʹmologiâ, 2014
Purpose: to evaluate the efficacy and safety of the immunosuppressive therapy for severe forms of non-infections uveitis and retinovasculitis.Methods: 107 patients (62 males and 45 females aged 9 to 54 years) who received low dose methotrexate — 7.5-20 ...
E. A. Drozdova
doaj   +3 more sources

New-onset epilepsy in a patient with myelin oligodendrocyte glycoprotein antibodies [PDF]

open access: yesEncephalitis, 2021
In the literature, several adult cases with myelin oligodendrocyte glycoprotein (MOG) antibodies (Abs)-associated disorders have been reported to have seizure and acute disseminated encephalomyelitis (ADEM) as the main clinical manifestations, but the ...
Hansol Im, Taewon Kim
doaj   +1 more source

Off-label use of rituximab in dermatology: pemphigus treatment [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Since its approval in 1997 by the FDA (United States Food and Drug Administration), rituximab has been used for certain B-cell lymphomas and treatment-resistant rheumatoid arthritis.
Lislaine Bomm   +4 more
doaj   +1 more source

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