Off-label use of rituximab in dermatology: pemphigus treatment [PDF]
Since its approval in 1997 by the FDA (United States Food and Drug Administration), rituximab has been used for certain B-cell lymphomas and treatment-resistant rheumatoid arthritis.
Lislaine Bomm +4 more
doaj +1 more source
New drugs, new challenges for dermatologists: mucocutaneous ulcers secondary to everolimus [PDF]
Everolimus, a mammalian target of rapamycin inhibitor, is an emerging drug, which is being increasingly applied in oncology and solid organ transplantation. Oral ulcers are a frequent side effect associated with this immunosupressor.
Victor Pavan Pasin +5 more
doaj +1 more source
Safety and effectiveness of mycophenolate mofetil associated with tacrolimus for liver transplantation immunosuppression: a systematic review and meta-analysis of randomized controlled trials [PDF]
A combination of immunosuppressants may improve outcomes due to the synergistic effect of their different action mechanisms. Currently, there is no consensus regarding the best immunosuppressive protocol after liver transplantation.
Francisco Tustumi +11 more
doaj +1 more source
Refractory pemphigus vulgaris treated with rituximab and mycophenolate mofetil [PDF]
The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used.
Stephanie Del Rio Navarrete Biot +5 more
doaj +1 more source
Nonimmunologic targets of immunosuppressive agents in podocytes
Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis.
Tae-Hyun Yoo, Alessia Fornoni
doaj +1 more source
Imunossupressores na Dermatologia Immunosuppressive agents in Dermatology
Os imunossupressores são drogas que agem na divisão celular e têm propriedades anti-inflamatórias. Sendo assim, são essencialmente prescritos na prevenção de rejeição de transplantes e no tratamento das doenças autoimunes e inflamatórias crônicas, que ...
Aline Lopes Bressan +3 more
doaj +1 more source
The utility of animal models in developing immunosuppressive agents [PDF]
The immune system comprises an integrated network of cellular interactions. Some responses are predictable, while others are more stochastic. While in vitro the outcome of stimulating a single type of cell may be stereotyped and reproducible, in vivo ...
Martins, Paulo N. +4 more
core +1 more source
The susceptibility of baboons to the novel immunosuppressant, FTY720 [PDF]
Bibliography: leaves 109-118.Since there is a major scarcity of donor organs world-wide, the experimental search for human organs has focused on two alternatives; mechanical devices and cross-species transplants.
Semple, P L
core +1 more source
Immune Response to Vaccination in Patients with Psoriasis Treated with Systemic Therapies
Psoriasis is a chronic inflammatory skin disease usually treated with immunomodulatory/immunosuppressive agents. The use of these agents has been associated with an increased susceptibility to infections.
Andrea Chiricozzi +3 more
doaj +1 more source
TAFRO syndrome was effectively treated with an inexpensive novel scheme: A case report
A man diagnosed as TAFRO syndrome was successfully responded to a novel immunosuppressive regimen containing methylprednisolone and mycophenolate mofetil. Blood cells firstly recovered, followed by the general situation and complete recover 1 month later,
Shan Meng +7 more
doaj +1 more source

