Clinical efficacy of 0.05% cyclosporine nano-emulsion in the treatment of dry eye syndrome associated with meibomian gland dysfunction [PDF]
AIM: To evaluate the clinical efficacy of topical 0.05% cyclosporine nano-emulsion in the treatment of dry eye syndrome (DES) with meibomian gland dysfunction (MGD).
Yeon Ji Jo, Ji Eun Lee, Jong Soo Lee
doaj +1 more source
Arabic Gum Role in Ameliorating Cyclosporine- A Initiated Nephrotoxicity in Rats [PDF]
Background: Recently many researchers reported that treatment using cyclosporine A in extended period in order to avoide the rejection of allograft is connected with renal impairment progress.
Hosam-Eldin Osman +3 more
doaj +1 more source
The ameliorative effect of N-acetylecysteine on cyclosporine induced testicular toxicity in male albino rats [PDF]
Introduction: Cyclosporine A (CsA) is considered one of the potent drugs that are used extensively in organ transplant and oncology patients. It is also used in autoimmune diseases. Unfortunately, its use is accompanied with several hazards; one of these
Maha Hilal +4 more
doaj +1 more source
Experimental study of renal toxicity of cyclosporine and the ameliorative effect of N-acetylecysteine in albino rat [PDF]
Introduction: Cyclosporine A (CsA) is considered powerful immunosuppressive drug which has improved the quality of life and survival rate of transplant patients and also used in autoimmune diseases. However, its use is limited by many side effects mainly
Walaa Allam +4 more
doaj +1 more source
Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts. [PDF]
BACKGROUND: Immunosuppressant cyclosporine-A induces gingival hyperplasia, which is characterized by increased fibroblast proliferation and overproduction of extracellular matrix components and regulated by transforming growth factor-beta (TGF-β).
Yi Chung, Earl Fu
doaj +1 more source
Cyclosporine A (CsA) is a neutral lipophilic compound that was first isolated in the 1970s from the fungal species Tolypocladium inflatum gams. CsA is a cyclic polypeptide that consists of 11 amino acids and that has a molecular weight of 1202 daltons.1 It was found to have potent immunosuppressive properties and was initially used in the late 1970s to
Gupta, Aditya K. +7 more
openaire +3 more sources
Cyclosporine Affects the Main Virulence Factors of Cryptococcus neoformans In Vitro
This study aimed to investigate the effects of cyclosporine on the morphology, cell wall structure, and secretion characteristics of Cryptococcus neoformans.
Iara Bastos de Andrade +9 more
doaj +1 more source
Problems in pharmaceutical compounding of eye-drops with cyclosporine A [PDF]
Cyclosporine A is very effective in treatment of many ophthalmic pathologies like immunological and inflammatory diseases of the cornea, conjunctive or uvea. It is also used to prevent corneal graft rejection and to treat dry eye syndrome.
Eliza Katarzyna Wolska +2 more
doaj +1 more source
Involvement of oxidative species in cyclosporine-mediated cholestasis
Cyclosporine is an established medication for the prevention of transplant rejection. However, adverse consequences such as nephrotoxicity, hepatotoxicity, and cholestasis have been associated with prolonged usage. In cyclosporine-induced obstructive and
Bernard Nsengimana +4 more
doaj +1 more source
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole +12 more
wiley +1 more source

