Results 21 to 30 of about 78,829 (264)

Changes in the blood cyclosporine level after switching from voriconazole to isavuconazole in a patient with aplastic anemia: insights from physiologically based pharmacokinetic model simulation and the Adverse Event Reporting System database study

Frontiers in Microbiology
IntroductionIsavuconazole, a broad-spectrum triazole approved by the United States Food and Drug Administration (FDA) in 2015, moderately inhibits cytochrome P450 3A4.
Chihiro Shiraishi, Chihiro Shiraishi, Hideo Kato, Hideo Kato, Kazuko Ino, Takuya Iwamoto, Takuya Iwamoto   +6 more
doaj   +1 more source

Pure White Cell Aplasia and Immune Thrombocytopenia after Thymoma Resection: A Case Report and Review of the Literature

Case Reports in Hematology, 2022
We report a case of pure white cell aplasia (PWCA) postthymoma resection in a 74-year-old male presenting with a 2-week history of fevers, night sweats, and severe febrile neutropenia.
Michael Youssef, Tyler W. Stratton, Reid C. Gallant, Christine Young, Daniel Y. Li, Siavash Piran   +5 more
doaj   +1 more source

Cyclosporine

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Cyclosporine is an immunosuppressive agent used in the treatment of psoriasis. It shows its action through calcineurin inhibition and T-lymphocytes.
Nahide Onsun
doaj   +1 more source

Cyclosporine for omalizumab-refractory chronic urticaria: a report of five cases

Allergy, Asthma & Clinical Immunology, 2023
Background While both the AAAAI/ACAAI and the EAACI/GA2LEN/EuroGuiDerm/APAAACI guidelines recommend starting cyclosporine for patients with chronic urticaria who have had an inadequate response to omalizumab, many clinicians are hesitant to initiate ...
Anthony F. LaCava, Olajumoke O. Fadugba
doaj   +1 more source

Infliximab versus Cyclosporine Treatment for Severe Corticosteroid-Refractory Ulcerative Colitis: A Korean, Retrospective, Single Center Study

Gut and Liver, 2015
Background/AimsIn patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission.
doaj   +1 more source

Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs

Veterinary Sciences, 2015
Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant ...
Alison Diesel, Karen Moriello
doaj   +1 more source

Structure of Cyclosporine and Its Metabolites: Total Synthesis of Cyclosporine Metabolites Formed by Oxidation at Positions 4 and 9 of Cyclosporine. Preparation of Leucine-4-cyclosporine, (?-Hydroxy)-N-methyl-leucine-9-cyclosporine and Leucine-4-(?-hydroxy)-N-methyl-leucine-9-cyclosporine

CHIMIA, 1992
The syntheses of the cyclosporine metabolites Leu-4-cyclosporine (AM4N), (?-OH)MeLeu-9-cyciosporine (AM9) and Leu-4-(?-OH)MeLeu-cyclosporine (AM4N9) were completed. Aspartic acid was used as starting material to prepare peptides containing (?-OH)
Roland M. Wenger, Kurt Martin, Charles Timbers, Anne Tromelin   +3 more
doaj   +2 more sources

Efficacy and safety of cyclosporine-based regimens for primary immune thrombocytopenia: a systematic review and meta-analysis

Journal of International Medical Research, 2023
Objective To conduct a meta-analysis assessing the efficacy and safety of cyclosporine-based combinations for primary immune thrombocytopenia (ITP).
Xiaojing Li, Wenwei Zhu, Jizhang Bao, Jiekai Li, Yongming Zhou   +4 more
doaj   +1 more source

Cyclosporine Nephrotoxicity [PDF]

Toxicologic Pathology, 1986
Cyclosporine (CSA) is a new immunosuppressant which has selectivity for the immune system and is without systemic side effects at therapeutic doses. In contrast to the cytotoxic class of immunosuppressants, no myelotoxic, teratogenic, mutagenic, or carcinogenic effects were observed.
B, Ryffel, M J, Mihatsch
openaire   +2 more sources

Oral cyclosporine therapy for refractory severe vernal keratoconjunctivitis

Indian Journal of Ophthalmology, 2012
We report the success of oral cyclosporine therapy in a patient with severe vision-threatening vernal keratoconjunctivitis. A child presented with severe allergy which was not controlled with topical steroids, cyclosporine and mast cell stabilizers. Oral
Nikhil S Gokhale, Rohini Samant, Vishnu Sharma   +2 more
doaj   +1 more source