Results 21 to 30 of about 102,207 (305)

Oral administration of ginseng ameliorates cyclosporine-induced pancreatic injury in an experimental mouse model. [PDF]

PLoS ONE, 2013
BACKGROUND: This study was performed to investigate whether ginseng has a protective effect in an experimental mouse model of cyclosporine-induced pancreatic injury.
Sun Woo Lim, Kyoung Chan Doh, Long Jin, Shang Guo Piao, Seong Beom Heo, Yu Fen Zheng, Soo Kyung Bae, Byung Ha Chung, Chul Woo Yang   +8 more
doaj   +1 more source

Dramatic Deep and Durable Remission of Acute Fulminant Ulcerative Colitis Achieved with Cyclosporine in a Patient Who Failed the Induction Intravenous Phase of Cyclosporine

Case Reports in Gastroenterology, 2021
Medical rescue therapy for patients with severe steroid-refractory ulcerative colitis (UC) consists of intravenous (IV) cyclosporine or infliximab and remains limited.
Alicia Philippou, Anam Rizvi, Adam Steinlauf   +2 more
doaj   +1 more source

Changes in the blood cyclosporine level after switching from voriconazole to isavuconazole in a patient with aplastic anemia: insights from physiologically based pharmacokinetic model simulation and the Adverse Event Reporting System database study

Frontiers in Microbiology
IntroductionIsavuconazole, a broad-spectrum triazole approved by the United States Food and Drug Administration (FDA) in 2015, moderately inhibits cytochrome P450 3A4.
Chihiro Shiraishi, Chihiro Shiraishi, Hideo Kato, Hideo Kato, Kazuko Ino, Takuya Iwamoto, Takuya Iwamoto   +6 more
doaj   +1 more source

Cross-reactivities of cyclosporin G (NVa2 cyclosporin) and metabolites in cyclosporin A immunoassays

Clinical Chemistry, 1993
Abstract Immunoassays of cyclosporin A (CsA) have been routinely used to measure CsG. We investigated the cross-reactivities of CsG and its metabolites, as well as the proportion CsG constitutes in relation to total drug measured, for six CsG metabolites (GM1, GM9, GM4N, GM1c, GM1c9, GM19) in the following CsA assays: Sandimmune ...
R W, Yatscoff, L J, Langman, D F, LeGatt
openaire   +2 more sources

Cyclosporine for omalizumab-refractory chronic urticaria: a report of five cases

Allergy, Asthma & Clinical Immunology, 2023
Background While both the AAAAI/ACAAI and the EAACI/GA2LEN/EuroGuiDerm/APAAACI guidelines recommend starting cyclosporine for patients with chronic urticaria who have had an inadequate response to omalizumab, many clinicians are hesitant to initiate ...
Anthony F. LaCava, Olajumoke O. Fadugba
doaj   +1 more source

Case report: Cyclosporine A-induced extrapyramidal syndrome following hematopoietic stem cell transplantation

Frontiers in Neurology, 2023
IntroductionCyclosporine A-associated neurotoxicity has been reported in up to 40% of patients and its wide range of neurological adverse effects have been reported, ranging from mild tremors to fatal leukoencephalopathy.
Fatema Al-Amrani, Abdulhakeem Al Rawas, Eiman Al-Ajmi, Amna Al Futaisi   +3 more
doaj   +1 more source

Structure of Cyclosporine and Its Metabolites: Total Synthesis of Cyclosporine Metabolites Formed by Oxidation at Positions 4 and 9 of Cyclosporine. Preparation of Leucine-4-cyclosporine, (?-Hydroxy)-N-methyl-leucine-9-cyclosporine and Leucine-4-(?-hydroxy)-N-methyl-leucine-9-cyclosporine

CHIMIA, 1992
The syntheses of the cyclosporine metabolites Leu-4-cyclosporine (AM4N), (?-OH)MeLeu-9-cyciosporine (AM9) and Leu-4-(?-OH)MeLeu-cyclosporine (AM4N9) were completed. Aspartic acid was used as starting material to prepare peptides containing (?-OH)
Roland M. Wenger, Kurt Martin, Charles Timbers, Anne Tromelin   +3 more
doaj   +2 more sources

Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs

Veterinary Sciences, 2015
Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant ...
Alison Diesel, Karen Moriello
doaj   +1 more source

Cyclosporine

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Cyclosporine is an immunosuppressive agent used in the treatment of psoriasis. It shows its action through calcineurin inhibition and T-lymphocytes.
Nahide Onsun
doaj   +1 more source

Infliximab versus Cyclosporine Treatment for Severe Corticosteroid-Refractory Ulcerative Colitis: A Korean, Retrospective, Single Center Study

Gut and Liver, 2015
Background/AimsIn patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission.
doaj   +1 more source