Results 1 to 10 of about 78,468 (167)
Frontiers in Pharmacology, 2021 Due to the widely application of Cyclosporine A (CsA) as an immunosuppressant in clinic, it is necessary to study its potential toxicity. Therefore, we used zebrafish as a model animal to evaluate the toxicity of CsA on embryonic development. Exposure of
Mengqi Wan +11 more
doaj +1 more source
Treatment of ocular rosacea:comparative study of topical cyclosporine and oral doxycycline [PDF]
International Journal of Ophthalmology, 2015 AIM:To compare the effectiveness of topical cyclosporine A emulsion with that of oral doxycycline for rosacea associated ocular changes and dry eye complaints.METHODS:One hundred and ten patients with rosacea were screened.
Aysegul Arman +2 more
doaj +1 more source
Indian Journal of Paediatric Dermatology, 2023 Stevens–Johnson syndrome and toxic epidermal necrolysis are severe skin reactions seen commonly following exposure to drugs. The quest for the ideal drug to treat these conditions faces significant challenges.
Simran S Tuli +3 more
doaj +1 more source
Effects of cyclosporine on steroid-refractory dry eyes
Taiwan Journal of Ophthalmology, 2023 PURPOSE: The purpose is to compare the effects of cyclosporine (CsA) on the steroid-refractory mixed-type dry eye (MTDE) and aqueous deficient dry eye (ADDE). MATERIALS AND METHODS: We retrospectively enrolled 71 patients with levels 3 and 4 dry eye that
Wan-Lin Wu, Shu-Wen Chang
doaj +1 more source
Clinics in Dermatology, 1989 Cyclosporine A (CsA) is a neutral lipophilic compound that was first isolated in the 1970s from the fungal species Tolypocladium inflatum gams. CsA is a cyclic polypeptide that consists of 11 amino acids and that has a molecular weight of 1202 daltons.1 It was found to have potent immunosuppressive properties and was initially used in the late 1970s to
Gupta, Aditya K. +7 more
openaire +3 more sources
Трансплантология (Москва), 2022 Introduction. Orthotopic liver transplantation is the most radical method of treatment of hepatocellular carcinoma. The high recurrence rate limits the use of transplantation in patients with hepatocellular cancer.
O. D. Olisov +3 more
doaj +1 more source
Treatment of thrombotic thrombocytopenic purpura
Терапевтический архив, 2021 The review discusses approaches to treatment of acquired thrombotic thrombocytopenic purpuгa (aTTP). In patients with aTTP plasma exchanges, glucocorticosteroids allow to stop an acute attack of TTP, and use of rituximab allows to achieve remission.
Gennadii M. Galstyan +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2020 Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived ...
Xian Zhou +7 more
doaj +1 more source
Problems in pharmaceutical compounding of eye-drops with cyclosporine A [PDF]
Farmacja Polska, 2019 Cyclosporine A is very effective in treatment of many ophthalmic pathologies like immunological and inflammatory diseases of the cornea, conjunctive or uvea. It is also used to prevent corneal graft rejection and to treat dry eye syndrome.
Eliza Katarzyna Wolska +2 more
doaj +1 more source
Application of cyclosporine A in the treatment of chronic spontaneous urticaria
Pifu-xingbing zhenliaoxue zazhi, 2022 Cyclosporine A (CsA), an immune-suppressive agent, is effective in the treatment of chronic spontaneous urticaria (CSU). It is recommended as the three-line treatment for chronic urticaria and for patients with severe disease refractory to antihistamine ...
Shanshan OU +6 more
doaj +1 more source