Results 11 to 20 of about 92,418 (213)
The potential role of cyclosporine A in cancer treatment: a comprehensive literature review
Contemporary OncologyCyclosporine A (CsA) is widely used as an immunosuppressant in organ transplantation to improve graft survival and prevent tissue rejection. The impact of CsA on cancer progression is highly complex, influenced by the intricate relationship between ...
Adnan Fojnica +4 more
doaj +2 more sources
Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]
, 2012 End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P. +7 more
core +1 more source
Comparison of topical application of cyclosporine A to prednisolone in treatment of dry eye disease
Delta Journal of Ophthalmology, 2023 Background Dry eye disease (DED) is a common ophthalmic disorder which affects 5–50% of the global population. Aim The aim of this study was to compare the effects of topical application of cyclosporine A (CsA) to prednisolone in patients with DED ...
Marwa A Zaky +3 more
doaj +1 more source
Nano-selenium supplementation upregulate TLR-7, MyD88, NF-kB, and TRAF6 genes in thymus of Wistar rats following treatment with cyclosporine A [PDF]
Nanomedicine JournalObjective(s): Selenium Nanoparticles can modulate the function of the immune system and improve immunity. We investigate the expression of toll-like receptor-7 (TLR-7), myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa B (NF-κB ...
Nafiseh Rezvani +2 more
doaj +1 more source
Urticaria in children: pathogenetic mechanisms and the possibilities of modern therapy
Vestnik Dermatologii i Venerologii, 2017 The review collected the latest literature data on urticaria - one of the most frequent skin diseases in children, accompanied by the appearance of blisters.
A. V. Kudryavceva, K. A. Neskorodova
doaj +1 more source
Journal of Transplantation, 2012 The discovery and use of cyclosporine since its inception into clinical use in the late 1970s has played a major role in the advancement of transplant medicine. While it has improved rates of acute rejection and early graft survival, data on long-term survival of renal allografts is less convincing.
Dustin Tedesco, Lukas Haragsim
openaire +3 more sources
Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy
Drug Delivery, 2019 Self-nanoemulsifying drug delivery system (SNEDDS) have been considered as a promising platform for oral delivery of many BCS (biopharmaceutics classification system) class IV drugs, such as docetaxel (DTX).
Weiping Cui +7 more
doaj +1 more source
Pharmaceutics, 2020 The physiological protective mechanisms of the eye reduce the bioavailability of topically administered drugs above all for those with high molecular weight and /or lipophilic characteristics, such as Cyclosporine A (CyA).
Eleonora Terreni +6 more
doaj +1 more source
Cyclosporine a in recalcitrant pediatric dermatoses – A retrospective analysis of thirty children
Indian Journal of Paediatric Dermatology, 2020 Background: The therapeutic use of cyclosporine is gradually extending to various dermatoses including both in adults and children. There are meager studies from India supporting its safe use in pediatric dermatoses.
Nibedita Patro +2 more
doaj +1 more source
Drug Delivery, 2018 Dry eye syndrome (DES) is one of the most common disorders of the eye for which combined treatment includes modification of the ocular environment and pathogenic therapies.
Yinglan Yu +5 more
doaj +1 more source