Results 21 to 30 of about 114,705,798 (237)

Postoperative association between impaired renal function and vascular dysfunction in liver transplant recipients

open access: yes, 2022
Liver Transplantation, EarlyView.
Domenico A. Chavez   +8 more
wiley   +1 more source

A Case of Atrial Fibrillation from Cyclosporine Toxicity [PDF]

open access: yes, 2004
We describe the unusual occurrence of atrial fibrillation immediately after a seizure in a young patient with cyclosporine toxicity. The new onset atrial fibrillation was triggered by high levels of cyclosporine and possibly facilitated by the ...
Pramod Sanghi   +3 more
core  

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

open access: yesArthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali   +11 more
wiley   +1 more source

Cyclosporine A and steroid therapy in childhood steroid-resistant nephrotic syndrome

open access: yes, 2010
Gargah Tahar, Lakhoua M RachidDepartment of Pediatric Nephrology, Charles Nicolle Hospital, Tunis, TunisiaBackground: In children, idiopathic nephrotic syndrome (INS) is primarily treated using corticosteroids.
Lakhoua M Rachid, Gargah Tahar
core   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults with Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective To characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE). Methods We analyzed cross‐sectional data from 451 adults in the Approaches to Positive, Patient‐centered Experiences of ...
Sarah L. Patterson   +7 more
wiley   +1 more source

Chronic Spontaneous Urticaria Cyclosporine Treatment: Our Experience

open access: yes, 2016
Aim:Treatment of severe chronic autoimmune urticaria is difficult. In this study we aimed to investigate efficacy and safety of cyclosporine in patients with chronic urticaria.Material and Method:Twenty patients with chronic spontaneous urticaria whom ...
Seçil Saral   +5 more
core   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

open access: yesAdvanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk   +11 more
wiley   +1 more source

A Prospective Study of Cyclosporine A 0.1% Combined with Loteprednol 0.2% vs Cyclosporine A 0.05% Alone in the Treatment of Dry Eye

open access: yes, 2023
John Hovanesian,1 Thomas Chester,2 Robert C Sorenson3 1Harvard Eye Associates, Laguna Hills, CA, USA; 2Cleveland Eye Clinic, Cleveland, OH, USA; 3Inland Eye Specialists, Hemet, CA, USACorrespondence: John Hovanesian, Harvard Eye Associates, 23961 Calle ...
Hovanesian J, Sorenson RC, Chester T
core  

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

open access: yesAdvanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng   +15 more
wiley   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

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