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Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]

open access: yesPharmaceutics, 2021
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
doaj   +3 more sources

Predicting drug-target interactions using drug-drug interactions. [PDF]

open access: yesPLoS ONE, 2013
Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs.
Shinhyuk Kim, Daeyong Jin, Hyunju Lee
doaj   +5 more sources

The Influence of Pharmacogenetics on the Clinical Relevance of Pharmacokinetic Drug–Drug Interactions: Drug–Gene, Drug–Gene–Gene and Drug–Drug–Gene Interactions

open access: yesPharmaceuticals, 2021
Drug interactions are a well-known cause of adverse drug events, and drug interaction databases can help the clinician to recognize and avoid such interactions and their adverse events. However, not every interaction leads to an adverse drug event.
Martina Hahn, Sibylle C. Roll
doaj   +3 more sources

Pharmacokinetics and Drug Interactions [PDF]

open access: yesPharmaceutics
Adverse drug reactions—including those caused by drug–drug interactions (DDIs)—are a major cause of emergency department visits and subsequent hospitalizations in the United States, with studies estimating that 10–30% of these visits are drug-related [...
Min-Koo Choi, Im-Sook Song
doaj   +2 more sources

PRELIMINARY INVESTIGATION ON THE PRODUCTION OF SURFACE ACTIVE COMPOUNDS WITH ANTIMICROBIAL AND EMULSIFYING PROPERTIES BY BACILLUS CLAUSII AND LACTOBACILLUS RHAMNOSUS PROBIOTIC STRAINS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2021
Surface active compounds (SACs) of bacterial origin are amphiphilic heteropolymers that may alter the interaction of gas-liquid, solid-liquid, and immiscible liquids surfaces, decrease the surface and interfacial tensions of liquids, and form stable ...
Marcus Dias-Souza   +2 more
doaj   +1 more source

Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding [PDF]

open access: yesPeerJ, 2018
The structure-thermodynamics correlation analysis was performed for a series of fluorine- and chlorine-substituted benzenesulfonamide inhibitors binding to several human carbonic anhydrase (CA) isoforms.
Alexey Smirnov   +4 more
doaj   +2 more sources

Prevalence and Clinical Significance of Drug–Drug and Drug–Dietary Supplement Interactions among Patients Admitted for Cardiothoracic Surgery in Greece

open access: yesPharmaceutics, 2021
Background: Drug interactions represent a major issue in clinical settings, especially for critically ill patients such as those with cardiovascular disease (CVD) who require cardiothoracic surgery (CTS) and receive a high number of different medications.
Marios Spanakis   +4 more
doaj   +1 more source

A comprehensive evaluation of potentially significant drug-drug, drug-herb, and drug-food interactions among cancer patients receiving anticancer drugs

open access: yesBMC Cancer, 2022
Introduction During the cancer treatment path, cancer patients use numerous drugs, including anticancer, supportive, and other prescribed medications, along with herbs and certain products.
Amer A. Koni   +8 more
doaj   +1 more source

Drug-drug interactions of tacrolimus [PDF]

open access: yesHospital Pharmacology, 2015
Introduction: Tacrolimus, potent immunosupressive drug, has large inter- and intraindividual pharmacokinetic variability. The aim: The aim of this current topic is to describe the importance of tacrolimus drug-drug interactions.
Rančić Nemanja K.   +4 more
doaj   +1 more source

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