Results 31 to 40 of about 142,539 (313)

Efficacy and safety of cyclosporine-based regimens for primary immune thrombocytopenia: a systematic review and meta-analysis

open access: yesJournal of International Medical Research, 2023
Objective To conduct a meta-analysis assessing the efficacy and safety of cyclosporine-based combinations for primary immune thrombocytopenia (ITP).
Xiaojing Li   +4 more
doaj   +1 more source

Oral cyclosporine therapy for refractory severe vernal keratoconjunctivitis

open access: yesIndian Journal of Ophthalmology, 2012
We report the success of oral cyclosporine therapy in a patient with severe vision-threatening vernal keratoconjunctivitis. A child presented with severe allergy which was not controlled with topical steroids, cyclosporine and mast cell stabilizers. Oral
Nikhil S Gokhale   +2 more
doaj   +1 more source

Infliximab versus Cyclosporine Treatment for Severe Corticosteroid-Refractory Ulcerative Colitis: A Korean, Retrospective, Single Center Study

open access: yesGut and Liver, 2015
Background/AimsIn patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission.
doaj   +1 more source

Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs

open access: yesVeterinary Sciences, 2015
Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant ...
Alison Diesel, Karen Moriello
doaj   +1 more source

FK506 IN PEDIATRIC KIDNEY-TRANSPLANTATION - PRIMARY AND RESCUE EXPERIENCE [PDF]

open access: yes, 1995
Between December 14, 1989, and December 17, 1993,43 patients undergoing kidney transplantation alone at the Children’s Hospital of Pittsburgh received FK506 as the primary immunosuppressive agent. The mean recipient age was 10.2 ± 4.8 years (range 0.7–17.
ELLIS, D   +13 more
core   +1 more source

Structure of Cyclosporine and Its Metabolites: Total Synthesis of Cyclosporine Metabolites Formed by Oxidation at Positions 4 and 9 of Cyclosporine. Preparation of Leucine-4-cyclosporine, (?-Hydroxy)-N-methyl-leucine-9-cyclosporine and Leucine-4-(?-hydroxy)-N-methyl-leucine-9-cyclosporine

open access: yesCHIMIA, 1992
The syntheses of the cyclosporine metabolites Leu-4-cyclosporine (AM4N), (?-OH)MeLeu-9-cyciosporine (AM9) and Leu-4-(?-OH)MeLeu-cyclosporine (AM4N9) were completed. Aspartic acid was used as starting material to prepare peptides containing (?-OH)
Roland M. Wenger   +3 more
doaj   +2 more sources

Cyclosporine Nephrotoxicity [PDF]

open access: yesToxicologic Pathology, 1986
Cyclosporine (CSA) is a new immunosuppressant which has selectivity for the immune system and is without systemic side effects at therapeutic doses. In contrast to the cytotoxic class of immunosuppressants, no myelotoxic, teratogenic, mutagenic, or carcinogenic effects were observed.
B, Ryffel, M J, Mihatsch
openaire   +2 more sources

Effect of cyclosporine on hepatic energy status and on fructose metabolism after portacaval shunt in dog as monitored by phosphorus‐31 nuclear magnetic resonance spectroscopy in vivo [PDF]

open access: yes, 1991
The effect of cyclosporin A on the hepatic energy status and intracellular pH of the liver and its response to a fructose challenge has been investigated using in vivo phosphorus‐31 nuclear magnetic resonance spectroscopy in dogs.
Atkinson   +37 more
core   +1 more source

Cyclosporine Improves Sleep Quality in Patients with Atopic Dermatitis

open access: yesDermatology and Therapy, 2020
Introduction Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease characterized by eczema and pruritus, and frequently impairs sleep quality.
Ken-ichi Yasuda   +6 more
doaj   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

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