Results 1 to 10 of about 185,590 (309)
The effects of casticin and myricetin on liver damage induced by methotrexate in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): In this study, we evaluated the therapeutic effects of casticin and myricetin on liver damage induced by methotrexate in rats.Materials and Methods: Thirty-six male rats were used for the study and divided into 6 groups: control ...
Fazile Nur Eki̇nci̇-Akdemi̇r +6 more
doaj +3 more sources
Brazilian Journal of Pharmaceutical Sciences, 2021 To find the predictors of High Dose Methotrexate toxicities in childhood Acute Lymphoblastic Leukemia Patients. This study included 198 Childhood Acute Lymphoblastic Leukemia patients (303 infusions) who were treated with High Dose Methotrexate ...
Yuxia Shan +6 more
doaj +1 more source
The Journal of Pediatric Academy, 2022 Methotrexate that has a safe and inexpensive profile is a first choice of juvenile idiopathic arthritis treatment. Nevertheless, gastrointestinal symptoms are not serious but common side effects of methotrexate.
Zahide Ekici Tekin +11 more
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A Rare Case of Methotrexate Induced Pancreatitis in Ectopic Pregnancy
The Ewha Medical Journal, 2023 Ectopic pregnancy (EP) refers to blastocyst implantation outside the uterine endometrium. EP is major cause of maternal morbidity and mortality. Treatment options include surgery, medical therapy with methotrexate,
Jiwon Choi +4 more
doaj +1 more source
Harmine Has Nephroprotective Effect Against Methotrexate-Induced Injury in Mice via Inhibition of Oxidative Stress [PDF]
Research Journal of Pharmacognosy, 2021 Background and objectives: Despite clinical use, the efficacy of methotrexate is often limited by some adverse effects, mainly nephrotoxicity. The most common mechanism of methotrexate-induced kidney damages is oxidative stress.
Cyrus Jalili +5 more
doaj +1 more source
Effect of methotrexate on neurobehavior and cholinesterase in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2023 This reading aimed to determine the therapeutic index of methotrexate (MTX) with a note on the consequence of methotrexate in chicks on neurobehavioral in addition to calculating the activity for cholinesterase in plasma and brain in chicks.
Maab A. Fadel +2 more
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Rheumatology and Therapy, 2023 Introduction One target of rheumatoid arthritis (RA) treatment is to achieve early sustained remission; over the long term, patients in sustained remission have less structural joint damage and physical disability.
Paul Emery +14 more
doaj +1 more source
Clinics, 2016 OBJECTIVE: To test the hypothesis that intravenous use of methotrexate associated with lipid nanoemulsions can achieve superior anti-inflammatory effects in the joints of rabbits with antigen-induced arthritis compared with commercial methotrexate ...
Suzana B.V. Mello +4 more
doaj +1 more source
Prenatal Effect of Methotrexate Exposure on the Fetal Brain of Albino Rats and the Possible Protective Role of Folic Acid [PDF]
Zagazig University Medical Journal, 2019 Background: Methotrexate is a folate antagonist, used to treat several diseases by interfering with cell growth. The objective of this study was to evaluate the effect of methotrexate on rat fetal telencephalon and the protective role of folic acid ...
Lamis Elsayed +3 more
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The Possible Ameliorative effect of Zafirlukast on Renal Toxicity Induced by Methotrexate in Experimental Animals [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2016 Methotrexate is a chemotherapeutic agent. Nephrotoxicity is an important side effect of treatment with methotrexate. Zafirlukast is a cystenyl leukotriene antagonist that acts as an anti-inflammatory and antioxidant agent.
Rasha Ahmed +2 more
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