Results 21 to 30 of about 185,590 (309)

Medical system error causing methotrexate poisoning and delay in diagnosis: report of two cases

Journal of Emergency Practice and Trauma, 2021
Objective: We are going to alert the emergency physicians to be aware of drugs side effects. Some drugs like methotrexate are not routine drugs, and the symptoms may be miss diagnosed if not completely notified.
Hamidreza Reihani
doaj   +1 more source

EXACERBATION OF ANKYLOSING SPONDYLITIS AFTER LOW-DOSE METHOTREXATE THERAPY

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Efficacy of methotrexate in ankylosing spondylitis (AS) is disputable. Nevertheless, methotrexate is still used for disease-modifying therapy of AS. Aim: To assess efficacy and safety of methotrexate in AS patients.
A. V. Orlov-Morozov
doaj   +1 more source

Methotrexate treatment in early psoriatic arthritis in comparison to rheumatoid arthritis: an observational nationwide study

RMD Open, 2023
Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other disease-modifying antirheumatic drug (DMARD)-changes), and ...
Ulf Lindström, Tor Olofsson, Lennart Jacobsson, Daniela Di Giuseppe, Eva Klingberg, Sofia Exarchou, Gerd-Marie Alenius, Johan K Wallman   +7 more
doaj   +1 more source

Failure Rate of Single Dose Methotrexate in Managment of Ectopic Pregnancy

Obstetrics and Gynecology International, 2015
Background. One of the treatment modalities for ectopic pregnancy is methotrexate. The purpose of this study is to identify the failure rate of methotrexate in treating patients with ectopic pregnancy as well as the risk factors leading to treatment ...
Feras Sendy, Eman AlShehri, Amani AlAjmi, Elham Bamanie, Surekha Appani, Taghreed Shams   +5 more
doaj   +1 more source

Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS

Asian Journal of Pharmaceutical Sciences, 2017
The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats.
Huiyan Shi, Chenzhi Hou, Liqiang Gu, Zhe Wei, Hang Xing, Meiyu Zhang, Shixiao Wang, Longshan Zhao, Kaishun Bi, Xiaohui Chen   +9 more
doaj   +1 more source

Methotrexate in Rheumatoid Arthritis [PDF]

, 1988
Over the past few years 'low dose pulse' methotrexate has gained increasing popularity as an effective treatment for refractory rheumatoid arthritis. Methotrexate has been shown to be better than placebo in controlled clinical trials.
Brooks, P. M.
core   +1 more source

Methotrexate mediates the integrity of intestinal stem cells partly through nitric oxide-dependent Wnt/β-catenin signaling in methotrexate-induced rat ileal mucositis

Journal of Pharmacological Sciences, 2022
This study aimed to elucidate the role of nitric oxide (NO) in intestinal stem cells in methotrexate-induced ileal mucositis in rats. Methotrexate induced the mRNA expressions of the Wnt/β-catenin target genes Wnt3a, Sox9, and Lgr5 and the Wnt-antagonist
Maiko Machida, Takuji Machida, Masaki Kikuchi, Ayaka Shimizu, Syunsuke Ida, Yoshiki Tawaraya, Risa Kato, Keisuke Haramaki, Kaori Yama, Saki Shiga, Masahiko Hirafuji, Kenji Iizuka   +11 more
doaj   +1 more source

Methotrexate-intolerance: Physician and parent assessment.

, 2019
Methotrexate-intolerance: Physician and parent assessment.
Peder Skov Wehner (3633574), Troels Herlin (4956082), Torben Stamm Mikkelsen (6945041), Karsten Nysom (5124536), Nini Kyvsgaard (6945038), Mikael Thastum (565937), Anne Estmann Christensen (6945044)   +6 more
core   +1 more source

Methotrexate-induced metabolic changes lead to increased extra-cellular adenosine

, 2011
Copyright information:Taken from "Molecular action of methotrexate in inflammatory diseases"Arthritis Research 2002;4(4):266-273.Published online 19 Mar 2002PMCID:PMC128935.Copyright © 2002 BioMed Central Ltd ADA = adenosine deaminase; AICAR ...
Bruce N Cronstein (96330), Edwin SL Chan (28334)   +1 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source