Results 11 to 20 of about 137,213 (265)
The Possible Ameliorative effect of Zafirlukast on Renal Toxicity Induced by Methotrexate in Experimental Animals [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2016 Methotrexate is a chemotherapeutic agent. Nephrotoxicity is an important side effect of treatment with methotrexate. Zafirlukast is a cystenyl leukotriene antagonist that acts as an anti-inflammatory and antioxidant agent.
Rasha Ahmed +2 more
doaj +1 more source
EFFICACY OF FUROSEMIDE IN METHOTREXATE CLEARANCE IN PATIENTS TREATED WITH HIGH DOSE METHOTREXATE
Hematology, Transfusion and Cell Therapy, 2022 Objective: Methotrexate was first used in 1947 as a chemotherapeutic drug in the treatment of acute lymphoblastic leukemia (ALL). Methotrexate has been extensively explored as an anticancer drug since that time.
Saqib Khan +2 more
doaj +1 more source
Journal of Medical Case Reports, 2019 Background Methotrexate, an immunosuppressant, is widely used as the standard therapeutic drug for rheumatoid arthritis. With the increasing frequency of use of methotrexate, adverse effects of methotrexate have been reported, one of which is known as ...
Ryohei Ono +6 more
doaj +1 more source
Clinics, 2008 INTRODUCTION: Methotrexate, a folate antagonist, is a mainstay treatment for childhood acute lymphoblastic leukemia. It is also widely used in a low dose formulation to treat patients with rheumatoid arthritis.
Sampath Madhyastha +3 more
doaj +1 more source
METHOTREXATE USE IS SAFE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Folia Medica Indonesiana, 2017 Monitoring level of methotrexate is not only aimed at monitoring effectiveness, but also safety aspects of the administration of high-dose methotrexate because the use of high-dose methotrexate is one of the problems associated with toxicity in various ...
Febriansyah Nur Utomo +3 more
doaj +1 more source
Medical system error causing methotrexate poisoning and delay in diagnosis: report of two cases
Journal of Emergency Practice and Trauma, 2021 Objective: We are going to alert the emergency physicians to be aware of drugs side effects. Some drugs like methotrexate are not routine drugs, and the symptoms may be miss diagnosed if not completely notified.
Hamidreza Reihani
doaj +1 more source
EXACERBATION OF ANKYLOSING SPONDYLITIS AFTER LOW-DOSE METHOTREXATE THERAPY
Alʹmanah Kliničeskoj Mediciny, 2016 Background: Efficacy of methotrexate in ankylosing spondylitis (AS) is disputable. Nevertheless, methotrexate is still used for disease-modifying therapy of AS. Aim: To assess efficacy and safety of methotrexate in AS patients.
A. V. Orlov-Morozov
doaj +1 more source
RMD Open, 2023 Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other disease-modifying antirheumatic drug (DMARD)-changes), and ...
Ulf Lindström +7 more
doaj +1 more source
Failure Rate of Single Dose Methotrexate in Managment of Ectopic Pregnancy
Obstetrics and Gynecology International, 2015 Background. One of the treatment modalities for ectopic pregnancy is methotrexate. The purpose of this study is to identify the failure rate of methotrexate in treating patients with ectopic pregnancy as well as the risk factors leading to treatment ...
Feras Sendy +5 more
doaj +1 more source
Asian Journal of Pharmaceutical Sciences, 2017 The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats.
Huiyan Shi +9 more
doaj +1 more source