Results 1 to 10 of about 63,234 (249)

Azathioprine Inhibits Hepatitis A Virus Replication In Vitro [PDF]

Pathogens
Hepatitis A virus (HAV) infection can occasionally cause acute severe hepatitis. Patients with this disease sometimes need to undergo liver transplantation with immunosuppressants.
Tatsuo Kanda, Reina Sasaki-Tanaka, Hiroyuki Abe, Takeshi Yokoo, Akira Sakamaki, Kazunao Hayashi, Hiroteru Kamimura, Kenya Kamimura, Ryota Masuzaki, Hirofumi Kogure, Hiroaki Okamoto, Shuji Terai   +11 more
doaj   +2 more sources

Azathioprine

Reactions Weekly, 2012
Hoofnagle JH.
europepmc   +4 more sources

A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy [PDF]

Childhood Kidney Diseases, 2017
Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction.
Jae Choon Kim, Ye Kyung Kim, Hye Sun Hyun, Eu Jin Park, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong   +6 more
doaj   +1 more source

Sensing Methods of Immunosuppressant Drugs: Calcineurin Inhibitors and Purine Synthesis Inhibitor Agents [PDF]

ImmunoAnalysis, 2021
Today, immunosuppression is associated as a necessary protocol in renal posttransplantation follow-up to improve both patient and graft survival rates.
Zahra Golsanamlou, Jafar Soleymani, Abolghasem Jouyban   +2 more
doaj   +1 more source

Azathioprine versus beta interferons for relapsing-remitting multiple sclerosis: a multicentre randomized non-inferiority trial. [PDF]

PLoS ONE, 2014
For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Luca Massacesi, Irene Tramacere, Salvatore Amoroso, Mario A Battaglia, Maria Donata Benedetti, Graziella Filippini, Loredana La Mantia, Anna Repice, Alessandra Solari, Gioacchino Tedeschi, Clara Milanese   +10 more
doaj   +1 more source

Safety and Efficacy of Azathioprine as a Second Line Therapy for Primary Immune Thrombocytopenic Purpura

Journal of Nepal Medical Association, 2016
Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily
Bishesh Sharma Poudyal, Binaya Sapkota, Gentle Sunder Shrestha, Sujan Thapalia, Bishal Gyawali, Sampurna Tuladhar   +5 more
doaj   +3 more sources

Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity

Clinical and Translational Science, 2022
TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity.
Laura L. Daniel, Alyson L. Dickson, Jacy T. Zanussi, Tyne W. Miller‐Fleming, Peter S. Straub, Wei‐Qi Wei, W. Dale Plummer, William D. Dupont, Ge Liu, Prathima Anandi, Tyler S. Reese, Kelly A. Birdwell, Vivian K. Kawai, Adriana M. Hung, Nancy J. Cox, QiPing Feng, C. Michael Stein, Cecilia P. Chung   +17 more
doaj   +1 more source

IMMUNOTOXICITY EFFECT OF LAVENDER (Lavendula Spica) FLOWERS POWDER AND OIL ON AZATHIOPRINE INDUCED TOXICITY IN EXPERIMENTAL RATS [PDF]

مجلة دراسات و بحوث التربیة النوعیة, 2016
Objective: The present study aims to investigate the possible protective effects of lavender flowers powder and oil alone to healthy rats and against azathioprine induced toxicity of immune in rats.
لبنى احمد شلباية, هناء فاروق المهيرى   +1 more
doaj   +1 more source

Azathioprine and 6-mercaptopurine-induced intrahepatic cholestasis of pregnancy: Case report and review of the literature

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: Azathioprine, a prodrug of 6-mercaptopurine (6-MP), is used in the treatment of inflammatory bowel disease and may be continued during pregnancy. Acute cholestatic liver injury has been reported to occur with azathioprine.
Maya Frank Wolf, Ronen Sloma, Luiza Akria, Eli Rimon, Yifat Wiener, Michal Carmiel Haggai, Lior Lowenstein   +6 more
doaj   +1 more source

Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma

iScience, 2021
Summary: Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor with poor survival rate. Temozolomide (TMZ) is used as standard chemotherapy to treat GBM, but a large number of patients either respond poorly and/or develop resistance ...
Hye Jin Nam, Young Eun Kim, Byoung-San Moon, Hyun Young Kim, Daeyoung Jung, Seungho Choi, Jeong Woon Jang, Do-Hyun Nam, Heeyeong Cho   +8 more
doaj   +1 more source