Results 21 to 30 of about 66,254 (246)

Azathioprine Hypersensitivity Syndrome: Two Cases of Febrile Neutrophilic Dermatosis Induced by Azathioprine

Case Reports in Dermatology, 2017
Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.
Majed Aleissa, Perrine Nicol, Marion Godeau, Emilie Tournier, Frederic de Bellissen, Marie-Angèle Robic, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Carle Paul   +8 more
doaj   +1 more source

Azathioprine Hypersensitivity Syndrome during Treatment of Severe Interstitial Lung Disease with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Case Reports in Pulmonology, 2020
Azathioprine is used to treat anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis. Azathioprine hypersensitivity syndrome is often missed.
Eri Nakano, Tomohiko Asakawa, Mea Asou, Eri Nohara, Tomoyuki Seki, Makoto Araki   +5 more
doaj   +1 more source

Effect of Aloe vera extract on some parameter liver functions changes and complete blood count induced by Azathioprine in male rats

Journal of Kerbala for Agricultural Sciences, 2023
The present study aimed to reveal the biological vitality of the immune suppressant medicine azathioprine (AZA), which has been used to treat immunological illnesses like acute lymphoblastic leukemia (ALL), inflammatory bowel disease, and organ ...
Ahmed Al-Hasnawi, Wafaa Kadhim Jasim
doaj   +1 more source

Azathioprine induced acute sialadenitis: A case report

Clinical Case Reports, 2023
Key clinical message Patients presenting with acute sialadenitis need careful review of their medications. Azathioprine is one of such drugs, which can rarely induce acute sialadenitis.
Priyanka Moovara Cackamvalli, Faten Mohammed Abdullah Al Bakri, Izzat Ali M. Khanjar   +2 more
doaj   +1 more source

Making the case for azathioprine, methotrexate, and cyclosporine in active vitiligo management [PDF]

Frontiers in Medicine
Yan Valle, Julia Sigova, Julia Sigova, Maria Borodina, Lyailya N. Kayumova, Liliya I. Almakaeva, Vladimir B. Pinegin, Konstantin Lomonosov   +7 more
doaj   +2 more sources

Role of oral corticosteroids, methotrexate, and azathioprine in patients with unstable vitiligo: A comparative study

Pigment International, 2022
Background: There are several medical and surgical interventions for vitiligo but still the search for a definite cure is going on. The first goal of the therapy is to make the disease stable by preventing the appearance of new lesions.
Niharika Mittal, Tejinder Kaur
doaj   +1 more source

Azathioprine shock [PDF]

Postgraduate Medical Journal, 1986
Summary Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and ...
openaire   +2 more sources

Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study. [PDF]

PLoS ONE, 2018
Azathioprine is a widely used immunosuppressive drug. Genetic polymorphisms and activity of the enzyme thiopurine methyltransferase (TPMT) have been associated with azathioprine efficacy and toxicity in several populations.
Arno C Hessels, Abraham Rutgers, Jan Stephan F Sanders, Coen A Stegeman   +3 more
doaj   +1 more source

Azathioprine favourably influences the course of malaria

Malaria Journal, 2009
Background Azathioprine triggers suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Eryptosis may accelerate the clearance of Plasmodium-infected erythrocytes.
Huber Stephan M, Föller Michael, Geiger Corinna, Koka Saisudha, Bobbala Diwakar, Lang Florian   +5 more
doaj   +1 more source

Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

Frontiers in Pharmacology, 2022
Despite the growing number of new drugs approved for the treatment of inflammatory bowel disease (IBD), the long-term clinical use of thiopurine therapy and the well-known properties of conventional drugs including azathioprine have made their place in ...
Slavica Lazarević, Maja Đanic, Hani Al-Salami, Armin Mooranian, Armin Mooranian, Momir Mikov   +5 more
doaj   +1 more source