Results 11 to 20 of about 76,298 (277)

Azathioprine Hypersensitivity Syndrome: Two Cases of Febrile Neutrophilic Dermatosis Induced by Azathioprine

Case Reports in Dermatology, 2017
Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.
Majed Aleissa, Perrine Nicol, Marion Godeau, Emilie Tournier, Frederic de Bellissen, Marie-Angèle Robic, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Carle Paul   +8 more
doaj   +2 more sources

Oral Tofacitinib versus Azathioprine in the Management of Chronic Actinic Dermatitis – An Open Randomized Clinical Trial [PDF]

Indian Dermatology Online Journal
Background: Chronic actinic dermatitis (CAD) is an immunologically mediated photodermatosis characterized by pruritic eczematous and lichenified plaques located predominantly on sun-exposed areas with notable sparing of eyelids, skin folds, and ...
Rishabh Singhal, Asma Arif Hussain, Varsha P. Jamale, Balkrishna P. Nikam, Prajakta A. Sharma   +4 more
doaj   +2 more sources

Azathioprine favourably influences the course of malaria [PDF]

Malaria Journal, 2009
Background Azathioprine triggers suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Eryptosis may accelerate the clearance of Plasmodium-infected erythrocytes.
Huber Stephan M, Föller Michael, Geiger Corinna, Koka Saisudha, Bobbala Diwakar, Lang Florian   +5 more
doaj   +2 more sources

Genetic risk variants in intestinal inflammatory disorders [PDF]

, 2010
PhDThis thesis includes work on the genetics of intestinal inflammatory disorders, concentrating on coeliac disease and Crohn’s disease. It explores how common genetic variants influence risk of complex phenotypes including immunological intolerance to
Dubois, Patrick Charles Alexander
core   +4 more sources

Azathioprine for atopic dermatitis

, 2001
For adults with atopic dermatitis (AD) refractory to topical treatment, the choices of second-line therapy are limited. Furthermore, there are concerns about the long-term safety of treatments such as cyclosporin.
Meggitt SJ, Reynolds NJ
core   +5 more sources

Azathioprine Hypersensitivity Syndrome during Treatment of Severe Interstitial Lung Disease with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Case Reports in Pulmonology, 2020
Azathioprine is used to treat anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis. Azathioprine hypersensitivity syndrome is often missed.
Eri Nakano, Tomohiko Asakawa, Mea Asou, Eri Nohara, Tomoyuki Seki, Makoto Araki   +5 more
doaj   +1 more source

Effectiveness of Echinacea purpurea extract on immune deficiency induced by azathioprine in male albino rats

Bioscience Journal, 2021
This study was performed to evaluate the effectiveness of Echinacea purpurea (E.P.) on azathioprine (AZA)-induced immune deficiency in albino rats. Thirty six male albino rats were divided into six equal groups.
Emad Mohamed El-Sherbiny, Hala Fawzy Osman, Mervat Sayed Taha   +2 more
doaj   +1 more source

Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine [PDF]

, 2010
Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns ...
Cordell, Samantha J., Sally A. Connolly, Dhandapani Ashok, Chris J. Taylor, Ashok, Dhandapani, Taylor, Chris J., Connolly, Sally A., Soman, Sherman, Samantha J. Cordell, Sherman Soman, Campbell, David I., David I. Campbell   +11 more
core   +1 more source

Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease [PDF]

, 2008
AIM:To investigate the efficacy of 6-mercaptopurine (6-MP) in cases of azathioprine (AZA) hypersensitivity in patients with inflammatory bowel disease. METHODS: Twenty nine previously confirmed Crohn’s disease (CD) (n = 14) and ulcerative colitis (UC)
Nagy, Ferenc, Lonovics, János, Farkas, Kaludia, Molnár, Tamás, Szepes, Zoltán, Nyári, Tibor András   +5 more
core   +1 more source

Detection of Hypoxanthine from Inosine and Unusual Hydrolysis of Immunosuppressive Drug Azathioprine through the Formation of a Diruthenium(III) System

Biosensors, 2021
Hypoxanthine (hpx) is an important molecule for both biochemistry research and biomedical applications. It is involved in several biological processes associated to energy and purine metabolism and has been proposed as a biomarker for a variety of ...
Marta Orts-Arroyo, Isabel Castro, José Martínez-Lillo   +2 more
doaj   +1 more source