Results 11 to 20 of about 66,254 (246)

Oral Tofacitinib versus Azathioprine in the Management of Chronic Actinic Dermatitis – An Open Randomized Clinical Trial [PDF]

Indian Dermatology Online Journal
Background: Chronic actinic dermatitis (CAD) is an immunologically mediated photodermatosis characterized by pruritic eczematous and lichenified plaques located predominantly on sun-exposed areas with notable sparing of eyelids, skin folds, and ...
Rishabh Singhal, Asma Arif Hussain, Varsha P. Jamale, Balkrishna P. Nikam, Prajakta A. Sharma   +4 more
doaj   +2 more sources

A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy [PDF]

Childhood Kidney Diseases, 2017
Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction.
Jae Choon Kim, Ye Kyung Kim, Hye Sun Hyun, Eu Jin Park, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong   +6 more
doaj   +1 more source

Safety and Efficacy of Azathioprine as a Second Line Therapy for Primary Immune Thrombocytopenic Purpura

Journal of Nepal Medical Association, 2016
Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily
Bishesh Sharma Poudyal, Binaya Sapkota, Gentle Sunder Shrestha, Sujan Thapalia, Bishal Gyawali, Sampurna Tuladhar   +5 more
doaj   +3 more sources

Azathioprine versus beta interferons for relapsing-remitting multiple sclerosis: a multicentre randomized non-inferiority trial. [PDF]

PLoS ONE, 2014
For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Luca Massacesi, Irene Tramacere, Salvatore Amoroso, Mario A Battaglia, Maria Donata Benedetti, Graziella Filippini, Loredana La Mantia, Anna Repice, Alessandra Solari, Gioacchino Tedeschi, Clara Milanese   +10 more
doaj   +1 more source

Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity

Clinical and Translational Science, 2022
TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity.
Laura L. Daniel, Alyson L. Dickson, Jacy T. Zanussi, Tyne W. Miller‐Fleming, Peter S. Straub, Wei‐Qi Wei, W. Dale Plummer, William D. Dupont, Ge Liu, Prathima Anandi, Tyler S. Reese, Kelly A. Birdwell, Vivian K. Kawai, Adriana M. Hung, Nancy J. Cox, QiPing Feng, C. Michael Stein, Cecilia P. Chung   +17 more
doaj   +1 more source

Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma

iScience, 2021
Summary: Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor with poor survival rate. Temozolomide (TMZ) is used as standard chemotherapy to treat GBM, but a large number of patients either respond poorly and/or develop resistance ...
Hye Jin Nam, Young Eun Kim, Byoung-San Moon, Hyun Young Kim, Daeyoung Jung, Seungho Choi, Jeong Woon Jang, Do-Hyun Nam, Heeyeong Cho   +8 more
doaj   +1 more source

Azathioprine and 6-mercaptopurine-induced intrahepatic cholestasis of pregnancy: Case report and review of the literature

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: Azathioprine, a prodrug of 6-mercaptopurine (6-MP), is used in the treatment of inflammatory bowel disease and may be continued during pregnancy. Acute cholestatic liver injury has been reported to occur with azathioprine.
Maya Frank Wolf, Ronen Sloma, Luiza Akria, Eli Rimon, Yifat Wiener, Michal Carmiel Haggai, Lior Lowenstein   +6 more
doaj   +1 more source

Azathioprine

Reactions Weekly
Keshavamurthy C, Patel P, Kassim TA.
europepmc   +3 more sources

Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis [PDF]

Anais Brasileiros de Dermatologia, 2015
We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of ...
Cristian Vera Kellet, Romina Andino Navarrete, Sergio González Bombardieri, Juan Manriquez   +3 more
doaj   +2 more sources

IMMUNOTOXICITY EFFECT OF LAVENDER (Lavendula Spica) FLOWERS POWDER AND OIL ON AZATHIOPRINE INDUCED TOXICITY IN EXPERIMENTAL RATS [PDF]

مجلة دراسات و بحوث التربیة النوعیة, 2016
Objective: The present study aims to investigate the possible protective effects of lavender flowers powder and oil alone to healthy rats and against azathioprine induced toxicity of immune in rats.
لبنى احمد شلباية, هناء فاروق المهيرى   +1 more
doaj   +1 more source