Results 11 to 20 of about 63,234 (249)
Prevention of thiopurine-induced early leukopenia in a Korean pediatric patient with Crohn’s disease who turned out to possess homozygous mutations in R139C [PDF]
Yeungnam University Journal of Medicine, 2020 Homozygous mutations in NUDT15 R139C are known as the major factor associated with thiopurine-induced early leukopenia, particularly in Asian patients. Therefore, NUDT15 genotyping is currently recommended before thiopurine treatment to identify patients
Jaewoan Bae, Byung-Ho Choe, Ben Kang
doaj +1 more source
Case Reports in Pulmonology, 2020 Azathioprine is used to treat anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis. Azathioprine hypersensitivity syndrome is often missed.
Eri Nakano +5 more
doaj +1 more source
Bioscience Journal, 2021 This study was performed to evaluate the effectiveness of Echinacea purpurea (E.P.) on azathioprine (AZA)-induced immune deficiency in albino rats. Thirty six male albino rats were divided into six equal groups.
Emad Mohamed El-Sherbiny +2 more
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Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis [PDF]
Anais Brasileiros de Dermatologia, 2015 We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of ...
Cristian Vera Kellet +3 more
doaj +2 more sources
Biosensors, 2021 Hypoxanthine (hpx) is an important molecule for both biochemistry research and biomedical applications. It is involved in several biological processes associated to energy and purine metabolism and has been proposed as a biomarker for a variety of ...
Marta Orts-Arroyo +2 more
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Acute-onset Alopecia in a Child: A Surrogate Marker of Azathioprine-induced Myelotoxicity
Indian Journal of Paediatric Dermatology, 2023 Azathioprine (AZA) is a widely used immunosuppressive which when not monitored cautiously can lead to life-threatening complications like myelotoxicity. In resource-limited countries, acute hair loss starting as early as 2 weeks after drug initiation can
Vibhu Mendiratta +2 more
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Efficacy and Safety of Rituximab in Immunobullous Diseases: A Retrospective Study from a Tertiary Care Centre of Nepal [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Rituximab is effective and safe treatment of immunobullous disorders. There are variations in doses of drugs used in different studies and uncertainties on when to use it along with use of adjuvant therapies. Efficacy and safety of this
Sudip Parajuli +3 more
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Case Reports in Dermatology, 2017 Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.
Majed Aleissa +8 more
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Postgraduate Medical Journal, 1986 Summary Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and ...
openaire +2 more sources
Use of thiopurines in inflammatory bowel disease: an update [PDF]
Intestinal Research, 2022 Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight.
Arshdeep Singh +25 more
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