Results 11 to 20 of about 71,298 (290)

Azathioprine Hypersensitivity Syndrome: Two Cases of Febrile Neutrophilic Dermatosis Induced by Azathioprine

Case Reports in Dermatology, 2017
Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.
Majed Aleissa, Perrine Nicol, Marion Godeau, Emilie Tournier, Frederic de Bellissen, Marie-Angèle Robic, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Carle Paul   +8 more
doaj   +2 more sources

Azathioprine Inhibits Hepatitis A Virus Replication In Vitro [PDF]

Pathogens
Hepatitis A virus (HAV) infection can occasionally cause acute severe hepatitis. Patients with this disease sometimes need to undergo liver transplantation with immunosuppressants.
Tatsuo Kanda, Reina Sasaki-Tanaka, Hiroyuki Abe, Takeshi Yokoo, Akira Sakamaki, Kazunao Hayashi, Hiroteru Kamimura, Kenya Kamimura, Ryota Masuzaki, Hirofumi Kogure, Hiroaki Okamoto, Shuji Terai   +11 more
doaj   +2 more sources

Azathioprine favourably influences the course of malaria

Malaria Journal, 2009
Background Azathioprine triggers suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Eryptosis may accelerate the clearance of Plasmodium-infected erythrocytes.
Huber Stephan M, Föller Michael, Geiger Corinna, Koka Saisudha, Bobbala Diwakar, Lang Florian   +5 more
doaj   +2 more sources

Azathioprine

Reactions Weekly, 2012
Hoofnagle JH.
europepmc   +4 more sources

A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy [PDF]

Childhood Kidney Diseases, 2017
Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction.
Jae Choon Kim, Ye Kyung Kim, Hye Sun Hyun, Eu Jin Park, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong   +6 more
doaj   +1 more source

Sensing Methods of Immunosuppressant Drugs: Calcineurin Inhibitors and Purine Synthesis Inhibitor Agents [PDF]

ImmunoAnalysis, 2021
Today, immunosuppression is associated as a necessary protocol in renal posttransplantation follow-up to improve both patient and graft survival rates.
Zahra Golsanamlou, Jafar Soleymani, Abolghasem Jouyban   +2 more
doaj   +1 more source

Azathioprine versus beta interferons for relapsing-remitting multiple sclerosis: a multicentre randomized non-inferiority trial. [PDF]

PLoS ONE, 2014
For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Luca Massacesi, Irene Tramacere, Salvatore Amoroso, Mario A Battaglia, Maria Donata Benedetti, Graziella Filippini, Loredana La Mantia, Anna Repice, Alessandra Solari, Gioacchino Tedeschi, Clara Milanese   +10 more
doaj   +1 more source

Safety and Efficacy of Azathioprine as a Second Line Therapy for Primary Immune Thrombocytopenic Purpura

Journal of Nepal Medical Association, 2016
Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily
Bishesh Sharma Poudyal, Binaya Sapkota, Gentle Sunder Shrestha, Sujan Thapalia, Bishal Gyawali, Sampurna Tuladhar   +5 more
doaj   +3 more sources

Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity

Clinical and Translational Science, 2022
TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity.
Laura L. Daniel, Alyson L. Dickson, Jacy T. Zanussi, Tyne W. Miller‐Fleming, Peter S. Straub, Wei‐Qi Wei, W. Dale Plummer, William D. Dupont, Ge Liu, Prathima Anandi, Tyler S. Reese, Kelly A. Birdwell, Vivian K. Kawai, Adriana M. Hung, Nancy J. Cox, QiPing Feng, C. Michael Stein, Cecilia P. Chung   +17 more
doaj   +1 more source

Azathioprine and 6-mercaptopurine-induced intrahepatic cholestasis of pregnancy: Case report and review of the literature

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: Azathioprine, a prodrug of 6-mercaptopurine (6-MP), is used in the treatment of inflammatory bowel disease and may be continued during pregnancy. Acute cholestatic liver injury has been reported to occur with azathioprine.
Maya Frank Wolf, Ronen Sloma, Luiza Akria, Eli Rimon, Yifat Wiener, Michal Carmiel Haggai, Lior Lowenstein   +6 more
doaj   +1 more source