Results 31 to 40 of about 66,254 (246)

Sensing Methods of Immunosuppressant Drugs: Calcineurin Inhibitors and Purine Synthesis Inhibitor Agents [PDF]

ImmunoAnalysis, 2021
Today, immunosuppression is associated as a necessary protocol in renal posttransplantation follow-up to improve both patient and graft survival rates.
Zahra Golsanamlou, Jafar Soleymani, Abolghasem Jouyban   +2 more
doaj   +1 more source

Protective effect of pumpkin seed oil against genotoxicity induced by azathioprine

Journal of Basic and Applied Zoology, 2012
Pumpkin is a leafy green vegetable; it belongs to the Cucurbitaceae family. Pumpkin seed oil supplementation can prevent changes in plasma lipids and blood pressure.
S.A. Elfiky, I.A. Elelaimy, A.M. Hassan, H.M. Ibrahim, R.I. Elsayad   +4 more
doaj   +1 more source

Azathioprine-induced marrow suppression in dermatology patients - Analysis of 18 patients

Indian Journal of Dermatology, 2022
Background: Azathioprine is an immunosuppressant used to treat several immunological disorders. As a purine analog, it inhibits DNA synthesis and cell multiplication. However, marrow suppression is a serious complication associated with azathioprine. Aim:
Vikrant V Saoji, Sugat A Jawade, Piyush Agrawal, Shravya Rimmalapudi   +3 more
doaj   +1 more source

A Case of Cutaneous Arthritis Differentiate from Drug Eruption

Journal of Hospital General Medicine, 2023
A 27-year-old woman with cervical lymphadenopathy and general malaise visited the otolaryngology department after developing a fever of 40 °C and pharyngeal pain.
Masao Nawata, MD, PhD, Yuya Fujita, MD, Atsushi Nagayasu, MD, Atsuko Yamamoto, MD, Aya Nawata, MD, PhD, Kazuyoshi Saito, MD, PhD   +5 more
doaj   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Influence of probiotics and deoxycholate on azathioprine transport in the PAMPA model: insights into pharmacomicrobiomics and interindividual variability in drug response

Frontiers in Pharmacology
IntroductionInterindividual variability in drug response presents a major clinical challenge, necessitating a deeper understanding of contributing factors.
Maja Đanić, Nebojša Pavlović, Natalija Dedić, Dragana Zaklan, Slavica Lazarević, Bojan Stanimirov, Momir Mikov   +6 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease

Case Reports in Gastrointestinal Medicine, 2020
Azathioprine is a cornerstone of the therapy of Crohn’s disease. Unfortunately, infections and malignancies are relatively common adverse effects related to this drug; however, cirrhosis is exceptionally reported as a side effect. We report the case of a
Jenny Roselli, Tommaso Innocenti, Erica Nicola Lynch, Laura Parisio, Giuseppe Macrì, Monica Milla, Tommaso Mello, Andrea Galli, Stefano Milani, Mirko Tarocchi   +9 more
doaj   +1 more source

The efficacy of immunosuppressive drugs induction therapy for lupus nephritis: a systematic review and network meta-analysis

Renal Failure, 2023
Objective This study was to assess the safety and effectiveness of immunosuppressive agents, specifically Voclosporin, when used in conjunction with mycophenolate mofetil (MMF) induction therapy for the management of lupus nephritis (LN).Methods A ...
Yongqiang Dong, Jinmin Shi, Shanshan Wang, Yanhong Liu, Shirong Yu, Lijun Zhao   +5 more
doaj   +1 more source

Prevention of thiopurine-induced early leukopenia in a Korean pediatric patient with Crohn’s disease who turned out to possess homozygous mutations in R139C [PDF]

Yeungnam University Journal of Medicine, 2020
Homozygous mutations in NUDT15 R139C are known as the major factor associated with thiopurine-induced early leukopenia, particularly in Asian patients. Therefore, NUDT15 genotyping is currently recommended before thiopurine treatment to identify patients
Jaewoan Bae, Byung-Ho Choe, Ben Kang
doaj   +1 more source