Results 51 to 60 of about 331,991 (309)

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Genetic polymorphism of interferon regulatory factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation.

PLoS ONE, 2014
BackgroundAlthough liver transplantation is one of the most efficient curative therapies of end stage liver diseases, recipients may suffer liver graft loss opst-operation. IRF-5, a member of Interferon Regulatory Factors, functions as a key regulator in
Xiaobo Yu, Bajin Wei, Yifan Dai, Min Zhang, Jian Wu, Xiao Xu, Guoping Jiang, Shusen Zheng, Lin Zhou   +8 more
doaj   +1 more source

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, EarlyView.
Objective Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source

The Effect of Genetic HLA Matching on Liver Transplantation Outcome: A Systematic Review and Meta-Analysis

Annals of Surgery Open, 2023
Objective:. We aim to investigate the effects of genetically based HLA matching on patient and graft survival, and acute and chronic rejection after liver transplantation Background:.
Gautam Kok, MD, PhD, Eveline F. Ilcken, MSc, Roderick H.J. Houwen, MD, PhD, Caroline A. Lindemans, MD, PhD, Edward E.S. Nieuwenhuis, MD, PhD, Eric Spierings, PhD, Sabine A. Fuchs, MD, PhD   +6 more
doaj   +1 more source

Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]

, 2005
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K, Bond, GJ, Macedo, C, Mazariegos, GV, Murase, N, Peters, J, Reyes, J, Sindhi, R, Starzl, TE   +8 more
core   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

C-reactive protein orchestrates acute allograft rejection in vascularized composite allotransplantation via selective activation of monocyte subsets

Journal of Advanced Research
Introduction: Despite advancements in transplant immunology and vascularized composite allotransplantation (VCA), the longevity of allografts remains hindered by the challenge of allograft rejection.
Jurij Kiefer, Johannes Zeller, Laura Schneider, Julia Thomé, James D. McFadyen, Isabel A. Hoerbrand, Friederike Lang, Emil Deiss, Balázs Bogner, Anna-Lena Schaefer, Nina Chevalier, Verena K. Horner, Sheena Kreuzaler, Ulrich Kneser, Martin Kauke-Navarro, David Braig, Kevin J. Woollard, Bohdan Pomahac, Karlheinz Peter, Steffen U. Eisenhardt   +19 more
doaj   +1 more source

Low CD4/CD8 Ratio in Bronchus-Associated Lymphoid Tissue Is Associated with Lung Allograft Rejection

Journal of Transplantation, 2012
Background. Bronchus-associated lymphoid tissue (BALT) has been associated with lung allograft rejection in rat transplant models. In human transplant recipients, BALT has not been linked to clinically significant rejection.
K. V. Shenoy, C. Solomides, F. Cordova, T. J. Rogers, D. Ciccolella, G. J. Criner   +5 more
doaj   +1 more source

Association of GPX1 Pro198Leu and SOD1 A251G polymorphisms with risk of acute kidney rejection [PDF]

Scripta Medica
Background/Aim: Acute rejection is one factor threatening the success of kidney transplantation. One of the factors that can cause graft rejection is oxidative stress.
Rayatpisheh Shima, Karimi Mohammad-Hossein, Saadat Iraj   +2 more
doaj   +1 more source

AIM2 as a putative target in acute kidney graft rejection

Frontiers in Immunology, 2022
Acute rejection (AR) is a process triggered via the recognition of grafted organ-derived antigens by the immune system, which could present as a life-threatening condition. In the context of a kidney transplant, despite improvement with immunosuppressive
Nathália Franchon Marques Tejada, João Vitor Ziroldo Lopes, Luis Eduardo Duarte Gonçalves, Izabela Mamede Costa Andrade da Conceição, Glória Regina Franco, Bruno Ghirotto, Niels Olsen Saraiva Câmara, Niels Olsen Saraiva Câmara   +7 more
doaj   +1 more source