Results 41 to 50 of about 108,325 (263)

Comparison of the Effect of Alemtuzumab versus Standard Immune Induction on Early Kidney Allograft Function in Shiraz Transplant Center

open access: yesInternational Journal of Organ Transplantation Medicine, 2015
Background: Induction therapy regimens classified as conventional immunosuppressive agents and lower doses of conventional agents combined with antibodies against T-cell antigens have been purposed to prevent acute rejection after renal transplantation ...
A Khalafi-Nezhad   +4 more
doaj  

Low CD4/CD8 Ratio in Bronchus-Associated Lymphoid Tissue Is Associated with Lung Allograft Rejection

open access: yesJournal of Transplantation, 2012
Background. Bronchus-associated lymphoid tissue (BALT) has been associated with lung allograft rejection in rat transplant models. In human transplant recipients, BALT has not been linked to clinically significant rejection.
K. V. Shenoy   +5 more
doaj   +1 more source

Association of GPX1 Pro198Leu and SOD1 A251G polymorphisms with risk of acute kidney rejection [PDF]

open access: yesScripta Medica
Background/Aim: Acute rejection is one factor threatening the success of kidney transplantation. One of the factors that can cause graft rejection is oxidative stress.
Rayatpisheh Shima   +2 more
doaj   +1 more source

Effects of antirejection therapies for early subclinical acute rejection in renal transplant protocol biopsies

open access: yesRenal Replacement Therapy, 2022
Background Although recently strengthened immunosuppression protocols have decreased the incidence of clinical acute rejection of renal transplants, subclinical acute rejection and borderline changes remain problematic.
Kei Sakurabayashi   +9 more
doaj   +1 more source

The molecular immunology of acute rejection: an overview

open access: yesTransplant Immunology, 1993
Abstract Transplantation immunology began as an empirical science but can now take its place as a discipline with a strong theoretical and molecular basis. The Laws of Transplantation, formulated at the beginning of this century by Little and Tyzzer, can be paraphrased as ‘Isografts succeed; allografts fail’.
Halloran, Philip F.   +3 more
openaire   +4 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

AIM2 as a putative target in acute kidney graft rejection

open access: yesFrontiers in Immunology, 2022
Acute rejection (AR) is a process triggered via the recognition of grafted organ-derived antigens by the immune system, which could present as a life-threatening condition. In the context of a kidney transplant, despite improvement with immunosuppressive
Nathália Franchon Marques Tejada   +7 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

open access: yesAdvanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt   +8 more
wiley   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

FEATURES OF CLINICAL DISPLAYS OF THE TRANSPLANTED HEART ACUTE REJECTION

open access: yesВестник трансплантологии и искусственных органов, 2010
In the present research features of current of clinical and structural changes are considered at acute rejection at the patients who have carried orthotopic transplantation of heart.
S. J. Shemakin   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy