Results 21 to 30 of about 108,325 (263)
Heparan sulfate is a plasma biomarker of acute cellular allograft rejection.
PLoS ONE, 2018 Despite advances in management of immunosuppression, graft rejection remains a significant clinical problem in solid organ transplantation. Non-invasive biomarkers of graft rejection can facilitate earlier diagnosis and treatment of acute rejection.
Andrew S Barbas +6 more
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Diagnosi e trattamento del rigetto acuto cellulo-mediato nel trapianto di rene
Giornale di Clinica Nefrologia e Dialisi, 2020 The incidence of acute rejection of the kidney allograft in the world has been around 15% during the period between 2001 and 2003. It is clinically defined as an elevation in the level of serum creatinine by more than 0.3 mg/dL and is diagnosed by kidney
Aris Tsalouchos, Maurizio Salvadori
doaj +1 more source
The impact of early acute rejection on kidney graft survival after repeat kidney transplantation
Трансплантология (Москва), 2021 Introduction. Despite the improvements in immunosuppressive therapy, the growing number of repeat kidney transplantations and associated risks of acute rejection make it relevant to assess the impact of early acute rejection on a long-term kidney graft ...
A. V. Pinchuk +5 more
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Mediators of Inflammation, 2015 Acute rejection is a major risk factor for chronic allograft injury (CAI). Blood leukocytes interacting with allograft endothelial cells during acute rejection were suggested to contribute to the still enigmatic pathogenesis of CAI.
Anna Zakrzewicz +3 more
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Pteridines, 1998 Levels of serum- and urinary-neopterin and serum-IL-6 and IL-6R of kidney transplant recipients "Were higher in acute rejection episode than in stable condition. IL-8 serum levels had risen prior to clinical diagnosis of acute rejection episode.
Miki Tsuneharu +2 more
doaj +1 more source
THE DIAGNOSIS OF LIVER ALLOGRAFT ACUTE REJECTION IN LIVER BIOPSIES
Вестник трансплантологии и искусственных органов, 2011 We performed histological examination of 80 liver allograft biopsies, the diagnosis of acute rejection was proved in 34 cases. Histological changes in liver biopsies in different grades of acute rejection were estimated according to Banff classification ...
L. V. Shkalova +5 more
doaj +1 more source
The Biology of Acute Transplant Rejection
Annals of Surgery, 1991 An intriguing and increasingly understood facet of immune responses is the ability of a recipient to destroy a foreign tissue or organ graft. The phenomenon of acute rejection of an allograft involves a series of complex and inter-related cellular and humoral events, culminating in graft death.
N L, Tilney, J W, Kupiec-Weglinski
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Incidence, Risk Factors, and Treatment Outcome of Acute Renal Allograft Rejection
Indian Journal of TransplantationBackground: Acute rejection occurs at any time following renal transplantation. The study aims to find the incidence, risk factors, and outcome of acute rejection in kidney transplantation. Materials and Methods: Retrospective cohort study conducted from
Remyasri Akhil +4 more
doaj +1 more source