Results 221 to 230 of about 1,197,646 (376)

Acute renal failure: definitions, diagnosis, pathogenesis, and therapy.

open access: yesJournal of Clinical Investigation, 2004
R. Schrier, Wei Wang, B. Poole, A. Mitra
semanticscholar   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang   +9 more
wiley   +1 more source

Kinetics of Serum-Free Light Chain Removal by High-Cutoff Hemodialysis in Patients with Multiple Myeloma and Acute Renal Failure. [PDF]

open access: yesMedicina (Kaunas)
Veldman WA   +6 more
europepmc   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

open access: yesAdvanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong   +15 more
wiley   +1 more source

Neonatal Spontaneous Abdominal Aortic Thrombosis Associated With Hypernatremic Dehydration and Acute Renal Failure: A Case Series. [PDF]

open access: yesClin Case Rep
Noor FA   +9 more
europepmc   +1 more source

Acute renal failure with chronic lymphocytic leukaemia [PDF]

open access: bronze, 1996
Alberto Martínez-Vea   +6 more
openalex   +1 more source

Recent advances in the pathophysiology of ischemic acute renal failure.

open access: yesJournal of the American Society of Nephrology, 2003
J. Bonventre, J. Weinberg
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

open access: yesAdvanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du   +6 more
wiley   +1 more source

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