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Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery [PDF]

open access: yesEBioMedicine, 2018
The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development.
Ugo Valbusa   +2 more
exaly   +4 more sources

Bioengineered Cystinotic Kidney Tubules Recapitulate a Nephropathic Phenotype. [PDF]

open access: yesCells, 2022
Nephropathic cystinosis is a rare and severe disease caused by disruptions in the CTNS gene. Cystinosis is characterized by lysosomal cystine accumulation, vesicle trafficking impairment, oxidative stress, and apoptosis. Additionally, cystinotic patients
Sendino Garví E   +2 more
europepmc   +2 more sources

Fine Structure of the Trunk Kidney and Distribution of Its Secreted Exosomes in the Adult Zebrafish

open access: yesShiyan dongwu yu bijiao yixue, 2023
Objective To observe the fine structure of the trunk kidney in zebrafish, and to identify its secreted exosomes.Methods The microstructure and ultrastructure of the trunk kidney in zebrafish were observed by light microscopy and electron microscopy, and ...
LIN Jinxing   +5 more
doaj   +1 more source

Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages

open access: yesShiyan dongwu yu bijiao yixue, 2023
ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages.MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected.
LU Lingqun   +4 more
doaj   +1 more source

Expression of Bcl-2 and Bax in mouse renal tubules during kidney development. [PDF]

open access: yesPLoS ONE, 2012
Bcl-2 and Bax play an important role in apoptosis regulation, as well as in cell adhesion and migration during kidney morphogenesis, which is structurally and functionally related to mitochondria.
Xiao-Feng Song   +4 more
doaj   +1 more source

Morphological description and histological structure of the Hedgehog Kidney (Hemiechinus auritus)

open access: yesTikrit Journal of Pure Science, 2023
This study was aimed to recognize the morphological description and histological structure of the kidney in hedgehog (Hemiechinus auritus). The morphological results showed that the kidney has a small bean shape and reddish brown color.
Thekra Atta   +4 more
doaj   +1 more source

The kidney of the Nodularia freshwater mussel has a larger filtration-size and counter-current system with improved water excretion compared with the seawater mussel Mytilus

open access: yesBiology Open, 2021
Histological studies and magnetic resonance imaging were employed to analyze the kidney structure and function of the freshwater mussel, Nodularia douglasiae. The Nodularia kidney consists of proximal, intermediate and distal tubules.
Eriko Seo   +2 more
doaj   +1 more source

The relationship between the lesions of kidneys and the different production stages in layers [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2009
In this study seventy case of dead layers from daily mortalities of farm were inspected and in different production stages. 33 cases suffered from renal pathological lesions distributed as 3 cases in preproduction stages, 24 cases in peak of production ...
A. H. Al-Hamadani, M. H. Mohammed
doaj   +1 more source

Effect of Fluoxetine on Kidney of Albino Rats- A Histological Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Fluoxetine and other Selective Serotonin Reuptake Inhibitors (SSRIs) are reported to produce hyponatremia especially in elderly patients. Aim: To evaluate histological changes in kidney tissue of albino rats by different doses of fluoxetine
Alka Aggarwal   +3 more
doaj   +1 more source

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