Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Bioinformatic identification of genes and mechanisms related to acute respiratory distress syndrome and sepsis: A bioinformatic study. [PDF]
Zhang R, Fu Y, Long F, Cheng Q.
europepmc +1 more source
Energetic dysregulations in psychotic disorders: Targets for new therapeutics
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson +10 more
wiley +1 more source
Aviptadil in Acute Respiratory Distress Syndrome-Promise or Mirage? [PDF]
Chanchalani G.
europepmc +1 more source
ABSTRACT Objective This study aimed to explore the thoughts and feelings of stroke patients and their carers (family/guardians) about oral care during hospitalisation, and (in turn) inform future research and service development. Background Stroke is a leading cause of adult disability and associated physical and cognitive impairments can compromise ...
Hazel Dickinson +3 more
wiley +1 more source
Risk Factors for Acute Respiratory Distress Syndrome in Sepsis Caused by Peptic Ulcer Perforation: A Retrospective Study. [PDF]
Kahraman YS +3 more
europepmc +1 more source
Haemophilia Management in Natural Disasters—From Field to Consensus Report
ABSTRACT Objective The earthquake in Türkiye had a profound impact on both haemophilia patients and healthcare services in the region. This experience highlighted the need for an effective action plan for patients with bleeding disorders in extraordinary situations.
Ahmet Muzaffer Demir +13 more
wiley +1 more source
Underreporting of acute kidney injury in randomized trials of acute respiratory distress syndrome with mortality endpoints: a systematic review. [PDF]
Passos RDH +9 more
europepmc +1 more source
ABSTRACT Introduction Thrombocytopenia has heterogeneous mechanisms, including peripheral destruction, consumption, and reduced marrow production. This study developed an unsupervised global complete blood count/research‐use‐only/cell population data (CBC/RUO/CPD) phenotyping model and evaluated post hoc whether thrombocytopenia severity and clinically
Mohammad A. Altememi +5 more
wiley +1 more source
Right ventricular-protective ventilation in acute respiratory distress syndrome: phenotypes, monitoring and ventilatory management. [PDF]
Peng C, Yang L, Wu Y, Shang Y, Zou X.
europepmc +1 more source

