Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan +5 more
wiley +1 more source
Take a deep breath: managing the challenges of acute respiratory distress syndrome cases. [PDF]
Castillo-Angeles M, Salim A.
europepmc +1 more source
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
Expression of Concern: MiR-124-3p helps to protect against acute respiratory distress syndrome by targeting p65. [PDF]
Liang Y +9 more
europepmc +1 more source
ABSTRACT Aim To synthesise the available evidence related to nurses' pain assessment and management practices for patients with diagnosed mental health conditions. Design Mixed‐methods systematic review. Data Sources Medline, CINAHL, PsycINFO, SPORTDiscus and Psychology and Behavioural Sciences Collection.
Aaron Lapuz Alejandro +4 more
wiley +1 more source
Mechanical Power and Ventilator Variables in Patients With Acute Respiratory Distress Syndrome: A Pilot Prospective Cohort. [PDF]
Joshi Y, Kumar S, Gairola M.
europepmc +1 more source
Exploring Long‐Term Outcomes in Sepsis Survivors: A Prospective Cohort Study Across Acute Hospitals
ABSTRACT Introduction While sepsis survival rates have improved, long‐term consequences remain under‐recognised and support services limited. Survivors often face persistent physical, cognitive and psychological impairments that diminish their quality of life.
Katie O'Byrne +9 more
wiley +1 more source
Determinants of tidal recruitment/derecruitment assessed by electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients. [PDF]
Perez J +11 more
europepmc +1 more source
Critical Care Nurse Practitioner Outcomes: A Scoping Review of the Literature
ABSTRACT Aim To support the development of nursing‐sensitive indicators specific to this role. Background The role of the advanced critical care nurse practitioner is a relatively new role in the Irish healthcare system. The role is attributed to the provision of high‐quality care to patients.
Mary Ryder +4 more
wiley +1 more source
Complications in acute respiratory distress syndrome: a systematic review and meta-analysis. [PDF]
Granton D +14 more
europepmc +1 more source

