Results 231 to 240 of about 3,409,620 (281)

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

open access: yesImmunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan   +5 more
wiley   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

open access: yesImmunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton   +1 more
wiley   +1 more source

Expression of Concern: MiR-124-3p helps to protect against acute respiratory distress syndrome by targeting p65. [PDF]

open access: yesBiosci Rep
Liang Y   +9 more
europepmc   +1 more source

Nurses' Experiences of Pain Management for Patients With Diagnosed Mental Health Conditions: A Systematic Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To synthesise the available evidence related to nurses' pain assessment and management practices for patients with diagnosed mental health conditions. Design Mixed‐methods systematic review. Data Sources Medline, CINAHL, PsycINFO, SPORTDiscus and Psychology and Behavioural Sciences Collection.
Aaron Lapuz Alejandro   +4 more
wiley   +1 more source

Exploring Long‐Term Outcomes in Sepsis Survivors: A Prospective Cohort Study Across Acute Hospitals

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Introduction While sepsis survival rates have improved, long‐term consequences remain under‐recognised and support services limited. Survivors often face persistent physical, cognitive and psychological impairments that diminish their quality of life.
Katie O'Byrne   +9 more
wiley   +1 more source

Determinants of tidal recruitment/derecruitment assessed by electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients. [PDF]

open access: yesAm J Respir Crit Care Med
Perez J   +11 more
europepmc   +1 more source

Critical Care Nurse Practitioner Outcomes: A Scoping Review of the Literature

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To support the development of nursing‐sensitive indicators specific to this role. Background The role of the advanced critical care nurse practitioner is a relatively new role in the Irish healthcare system. The role is attributed to the provision of high‐quality care to patients.
Mary Ryder   +4 more
wiley   +1 more source

Complications in acute respiratory distress syndrome: a systematic review and meta-analysis. [PDF]

open access: yesCrit Care
Granton D   +14 more
europepmc   +1 more source

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