Results 81 to 90 of about 87,305 (225)

Progress Toward a Portable Artificial Lung: A Systematic Review

Artificial Organs, EarlyView.
Eight portable respiratory assist devices were identified. The CE‐marked MobyBox and the FDA‐approved Breethe OXY‐1 system are in clinical use. Each device is substantially minimized to allow ambulation, but further work is required to address challenges related to anticoagulant management and safe mobilization. Created in BioRender. Svendsen, A. (2026)
Maja Munk Svendsen, Clara Kjær Hendriksen, Lars Folkersen, Peter Juhl‐Olsen, Leila Louise Benhassen, Søren Nielsen Skov   +5 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Acute Respiratory Distress Syndrome (ARDS) After Nitric Acid Inhalation

Türk Yoğun Bakim Derneği Dergisi, 2014
Lung injury resulting from inhalation of chemical products continues to be associated with high morbidity and mortality. Concentrated nitric acids are also extremely corrosive fuming chemical liquids.
Gülay Kır, Gizem Avcı, Bektaş Akpolat, Leyla Veral   +3 more
doaj   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu, Hsiaohsuan Wang, Hsuanfu Kuo, Chiahung Yen, Modasang Hua, Chiayuan Chang, Zhiwei Xu, Ifan Liu, Chongchao Hsieh, Chihhsin Hsu, Chiayang Li, Shuchi Wang, Yunghsiang Chen, Menghsuan Cheng, Polen Liu   +14 more
wiley   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Acute respiratory distress syndrome (ARDS)

, 2019
Acute respiratory distress syndrome is underrecognized and has a >40% mortality in moderate-to-severe disease. Recognition utilizing the Berlin definition clarifies the mortality risk and drives treatment efforts maximizing survival. Lung protective strategies as well as neuromuscular blockade and prone positioning have been shown to have a survival ...
openaire   +2 more sources

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

Transplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez, Carla Niveyro, Pedro Andrés Villalba Apestegui, Victoria Isabel Martin, Lucila María Compañy Kec, María Cynthia Tomasino, Mariana del Carmen del Marull, Haydee Ingrid Bernard, Claudia Patricia Lorena Fernández, Flavia Marcela Pelech, Maria Fernanda Tosin, María Fernanda González‐Hobecker, Karen Beatrice Duranona, Angela Daiana Jara, Justus Cornely, Oliver A. Cornely, Jon Salmanton‐García   +16 more
wiley   +1 more source

Spectroscopic Approach to Capillary-Alveolar Membrane Damage Induced Acute Lung Injury

Canadian Respiratory Journal, 1999
BACKGROUND: Acute (or adult) respiratory distress syndrome (ARDS) is often associated with a high mortality rate in the critical care population. The term acute lung injury (ALI), a primitive phase of ARDS, was introduced by the European and American ...
Jing Wang, Luis Oppenheimer, Paola Fata, Julio Pintin, Ross Stimpson, Henry H Mantsch   +5 more
doaj   +1 more source

Retrospective Evaluation of the Association Between Mechanical Power and Outcome in Mechanically Ventilated Dogs from a Multicenter Database (2019–2025): 76 Cases

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To assess the association between mechanical power (MP) and survival in mechanically ventilated dogs with primary pulmonary parenchymal disease and to compare its prognostic performance against individual ventilator parameters and oxygenation indices. Design Retrospective, multicenter observational cohort study.
Tereza Stastny, Robert H. Markowitz, Dana J. Caldwell, Jiwoong Her, Rachel C. Clarkin‐Breslin, Carolina S. Graham, Jeong E. Park, Deborah C. Silverstein   +7 more
wiley   +1 more source