Monitoring patients with acute respiratory failure during non-invasive respiratory support to minimize harm and identify treatment failure. [PDF]
Crit CarePerez J, Brandan L, Telias I.
europepmc +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
An elderly woman with acute respiratory failure and diffuse pulmonary changes. [PDF]
Breathe (Sheff)Soo CI +6 more
europepmc +1 more source
Critical Electrochemistry Technologies Applicable in Space Exploration
Advanced Science, EarlyView.The available resources in space and discuss the application scenarios and challenges of electrochemical methods in four critical domains is analyzed: metallurgical processing of mineral resources, water resources utilization, carbon cycle management in extraterrestrial habitats, and electrical energy storage.
Ruisi Xu +4 more
wiley +1 more source
Association between blood urea nitrogen to albumin ratio and 28-day mortality in ICU patients with acute respiratory failure: a retrospective analysis of MIMIC-IV database. [PDF]
BMC Med Inform Decis MakLi Z, Xie J, He Q, Li C.
europepmc +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Association Between Albumin Corrected Anion Gap and 28-Day All-Cause Mortality in Patients With Acute Respiratory Failure in ICU: A Retrospective Study Based on the MIMIC-IV Database. [PDF]
Clin Respir JQu J, Tang X, Cheng Y, Xiong W, Zhao Y.
europepmc +1 more source
Advanced Science, EarlyView.Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du +7 more
wiley +1 more source
Acute Respiratory Failure Due to Mucous Plug in a Patient With Tropical Spastic Paraparesis. [PDF]
CureusHamza H +4 more
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Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source