Results 41 to 50 of about 704,383 (285)

Acute bilateral phrenic nerve neuropathy causing hypercapnic respiratory failure associated with checkpoint inhibitor immunotherapy

Respiratory Medicine Case Reports, 2021
We present two cases of acute hypercapnic respiratory failure due to diaphragmatic dysfunction secondary to bilateral phrenic nerve paralysis, in patients who were receiving immunotherapy for melanoma.
M. Srinivasan, A.M. Taylor, G.V. Long, G. Herkes, G.G. King   +4 more
doaj   +1 more source

Assessment of pulmonary edema: principles and practice [PDF]

, 2018
Pulmonary edema increasingly is recognized as a perioperative complication affecting outcome. Several risk factors have been identified, including those of cardiogenic origin, such as heart failure or excessive fluid administration, and those related to ...
Assaad, Sherif, Friedman, Malcolm B., Kratzert, Wolf B., Perrino, Albert, Shelley, Benjamin   +4 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

ETIOLOGICAL AND CLINICO-PARACLINICAL CORRELATIONS IN CASE OF CHILDREN’S ACUTE RESPIRATORY FAILURE [PDF]

Romanian Journal of Pediatrics, 2017
Introduction. Acute respiratory failure presents very high morbidity and mortality among the pediatric patients, being one of the most frequent causes of recurring to the emergency services and of hospitalization. Material and method.
Iulia Armean, Cristina Oana Marginean, Lorena Elena Melit   +2 more
doaj   +1 more source

Principles of Inhalation Therapy [PDF]

, 1973
With the increasing complexity of ventilatory equipment and the rapid development of new techniques for respiratory care, it has become progressively more difficult for the average physician to keep pace with clinical and technical advancements.
O\u27Donohue, Walter J., Jr.
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016

Journal of Intensive Care, 2018
Background Since the 2009 pandemic influenza, we have nationally established a committee of the extracorporeal membrane oxygenation (ECMO) project. This project involves adequate respiratory management for severe respiratory failure using ECMO.
Shinichiro Ohshimo, Nobuaki Shime, Satoshi Nakagawa, Osamu Nishida, Shinhiro Takeda, Committee of the Japan ECMO project   +5 more
doaj   +1 more source

Reduced adiponectin levels in patients with COVID‐19 acute respiratory failure: A case‐control study

Physiological Reports, 2021
Hypoadiponectinemia is speculated to play a key role in the relationship between obesity and COVID‐19 respiratory failure. However, only one study has examined adiponectin levels in COVID‐19 patients, and none have investigated adiponectin levels ...
Sean M. Kearns, Katelyn W. Ahern, James T. Patrie, William B. Horton, Thurl E. Harris, Alexandra Kadl   +5 more
doaj   +1 more source

Respiratory Therapy Modalities in the Treatment of Acute Respiratory Failure [PDF]

, 1978
Rapid advances have been made in the field of respiratory therapy in the past several years, resulting in an increasing sophistication and range of application.
Mathers, James A. L., Jr.
core   +1 more source

Direct admission to the intensive care unit from the emergency department and mortality in critically ill hematology patients [PDF]

, 2019
Background: The aim of this study was to assess the benefit of direct ICU admission from the emergency department (ED) compared to admission from wards, in patients with hematological malignancies requiring critical care.
Azoulay, Elie, Benoit, Dominique, Bruneel, Fabrice, Chevret, Sylvie, Demoule, Alexandre, Kouatchet, Achille, Lebert, Christine, Lemiale, Virginie, Meert, Anne-Pascale, Mirouse, Adrien, Mokart, Djamel, Nyunga, Martine, Perez, Pierre, Peyrony, Olivier, Pène, Frédéric   +14 more
core   +2 more sources