Results 31 to 40 of about 19,110 (167)

Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014

Emerging Infectious Diseases, 2016
During August 8, 2014–October 14, 2014, a total of 11 children with acute flaccid myelitis and distinctive neuroimaging changes were identified near Denver, Colorado, USA.
Negar Aliabadi, Kevin Messacar, Daniel M. Pastula, Christine C. Robinson, Eyal Leshem, James Sejvar, W. Allan Nix, M. Steven Oberste, Daniel R. Feikin, Samuel R. Dominguez   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Distinct characteristics on mixed infection of SARS-CoV-2 variants and other respiratory pathogens among patients with acute COVID-19 in central China

Frontiers in Cellular and Infection Microbiology
BackgroundReports on mixed infection with different severe acute respiratory syndrome coronavirus 2 variants and other respiratory pathogens in patients with acute coronavirus disease in China remain scarce.
Yiman Geng, Youhua Yuan, Xuhong Lin, Jingjing Wei, Qi Zhang, Xiaohuan Mao, Xiaohuan Zhang, Xiulei Zhang, Yuan Zhang, Jing Zhao, Fengxia Guo, Peiming Zheng   +11 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Risk of ARI among non-exclusively breastfed under-five passive smoker children: A hospital-based cross-sectional study of Nepal

Frontiers in Public Health, 2016
Background: As Nepal witnesses high burden of both acute respiratory infection and passive smoking among under-five children, studies on effect modification of exclusive breast feeding on passive smoking and acute respiratory infection carry huge ...
Pushpa eThapa, Achyut Raj Pandey, Rajaram eDhungana, Bihungum eBista, Barsha eThapa, Shiva Raj Mishra   +5 more
doaj   +1 more source

Etiological analysis of acute respiratory tract infection in Taizhou of Zhejiang Province from 2020 to 2021

Shanghai yufang yixue, 2022
ObjectiveWe examined the principal respiratory pathogens in patients with acute respiratory tract infection in Taizhou， Zhejiang Province during 2020‒2021 to provide evidence for prevention， diagnosis and treatment of acute respiratory tract infection ...
WANG Ziyi, WENG Jian, WANG Hongzhu, SHENG Ying, LI Guixia, CHEN Xikai, LI Congcong, GUAN Yaya, SHENG Ying, SHEN Weiwei   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Acute respiratory infection and its associated factors among children under-five years attending pediatrics ward at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: institution-based cross-sectional study

BMC Pediatrics, 2020
Background Acute respiratory infection is manifested by cough accompanied by short rapid breathing which may be associated with death especially when there are other co-morbidities.
Henok Dagne, Zewudu Andualem, Baye Dagnew, Asefa Adimasu Taddese   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source