Results 51 to 60 of about 4,323,505 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Donnelly, CA, Hedley, AJ, Chau, P, Kong, JHB, Ferguson, NM, Liu, SH, Thach, TQ, Tse, LY, Ho, LM, Ghani, AC, Anderson, RM, Chan, KP, Lam, TH, Tsang, T, Riley, S, AbuRaddad, LJ, Leung, GM, Fraser, C, Lau, EMC, Kong, James HB, Leung, Gabriel M, Ghani, Azra C, Liu, Shao-Haei, Chau, Patsy, Abu-Raddad, Laith J, Lam, Tai-Hing, Ferguson, Neil M, Fraser, Christophe, Lau, Edith MC, Ho, Lai-Ming, Anderson, Roy M, Chan, King-Pan, Riley, Steven, Hedley, Anthony J, Tse, Lai-Yin, Donnelly, Christl A, Tsang, Thomas, Thach, Thuan-Quoc   +37 more
core   +2 more sources

Risk of ARI among non-exclusively breastfed under-five passive smoker children: A hospital-based cross-sectional study of Nepal

Frontiers in Public Health, 2016
Background: As Nepal witnesses high burden of both acute respiratory infection and passive smoking among under-five children, studies on effect modification of exclusive breast feeding on passive smoking and acute respiratory infection carry huge ...
Pushpa eThapa, Achyut Raj Pandey, Rajaram eDhungana, Bihungum eBista, Barsha eThapa, Shiva Raj Mishra   +5 more
doaj   +1 more source

Anaemia in acute HIV-1 subtype C infection. [PDF]

, 2007
BACKGROUND: The high prevalence of anaemia and the increased morbidity and mortality associated with anaemia during AIDS has been well described yet there has been little information about anaemia and changes in haemoglobin levels during acute and early ...
Auld, Sara C, van Loggerenberg, Francois, Auld Sara C., Loggerenberg, Francois van, Sobieszczyk Magdalena E., Abdool Karim Salim S., Grobler Anneke, Grobler, Anneke, Anneke Grobler, Auld, Sara C., Itua Iriogbe, Mlisana, Koleka Patience., Iriogbe, Itua, Sobieszczyk, Magdalena E, van Loggerenberg, F, Mlisana, K, Iriogbe, Itua., Salim S Abdool Karim, Mlisana, Koleka, Auld, SC, Abdool Karim, Salim Safurdeen., Sobieszczyk, ME, Grobler, A, Magdalena E Sobieszczyk, Williamson, Carolyn., Carolyn Williamson, Francois van Loggerenberg, Abdool Karim, Salim S, Sobieszczyk, Magdalena E., Iriogbe, I, Williamson Carolyn, Abdool Karim, SS, Sara C Auld, Team, for the CAPRISA Acute Infection Study, Williamson, Carolyn, Williamson, C, Grobler, Anna Christina., van Loggerenberg, Francois., van Loggerenberg Francois, Karim, Salim S Abdool, Koleka Mlisana, Iriogbe Itua, Mlisana Koleka, CAPRISA Acute Infection Study Team   +43 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Acute respiratory infection and its associated factors among children under-five years attending pediatrics ward at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: institution-based cross-sectional study

BMC Pediatrics, 2020
Background Acute respiratory infection is manifested by cough accompanied by short rapid breathing which may be associated with death especially when there are other co-morbidities.
Henok Dagne, Zewudu Andualem, Baye Dagnew, Asefa Adimasu Taddese   +3 more
doaj   +1 more source

IgG Seroconversion and Pathophysiology in Severe Acute Respiratory Syndrome Coronavirus 2 Infection

, 2021
We investigated the dynamics of seroconversion in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. During March 29–May 22, 2020, we collected serum samples and associated clinical data from 177 persons in London, UK, who had SARS ...
Staines, Henry M., Augustin, Yolanda, Planche, Tim, Sall, Amadou A., Cuevas, Luis E., Duvoix, Annelyse, Eckersley, Nicholas M., Monahan, Irene, Cubas-Atienzar, Ana I., Williams, Christopher T., Woolston, Kevin, Fraser, Alice J., Garrod, Gala, Moore, Catherine M., Davis, Paul, Owen, Sophie I., Cocozza, Michael, Johnson, Michael, Sainter, Chris, Kirwan, Daniela E., Hadcocks, Linda, Menzies, Stefanie, Davis, Mark, Hu, Qinxue, Wilkins, John, Byrne, Rachel L., Krishna, Sanjeev, Cusinato, Martina, Nebe-von-Caron, Gerhard, Schouten, James, Clark, David J., Macallan, Derek C., Mensah-Kane, Josephine, Kay, Grant A, Klekotko, Kesja, Forton, Daniel, Lewis, Zawditu, Fitchett, Joseph R.A., Adams, Emily R., Davies, Benedict M.O.   +39 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Acute and post-acute respiratory complications of SARS-CoV-2 infection: population-based cohort study in South Korea and Japan

Nature Communications
Considering the significant burden of post-acute COVID-19 conditions among patients infected with SARS-CoV-2, we aimed to identify the risk of acute respiratory complications or post-acute respiratory sequelae.
Yujin Choi, Hyeon Jin Kim, Jaeyu Park, Myeongcheol Lee, Sunyoung Kim, Ai Koyanagi, Lee Smith, Min Seo Kim, Masoud Rahmati, Hayeon Lee, Jiseung Kang, Dong Keon Yon   +11 more
doaj   +1 more source

Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru [PDF]

, 2015
The disease burden and risk factors for respiratory syncytial virus (RSV) and human metapneumovirus (MPV) infections among children living in remote, rural areas remain unclear.; We conducted a prospective, household-based cohort study of children aged ...
Gil, Ana I., Philip J Budge, Kathryn M. Edwards (534416), Verastegui, Hector, Yuwei Zhu, Hector Verastegui, Grijalva, Carlos G, Carlos G. Grijalva, Grijalva, Carlos G., Stella Hartinger, Stella Hartinger (759804), Gil, Ana I, Marie R Griffin, Griffin, Marie R., Wu, Andrew, Lanata, Claudio F., Marie R. Griffin (209725), Marie R. Griffin, Monika Johnson, Ana I. Gil, Philip J. Budge (389401), Williams, John, Andrew Wu, Carlos G. Grijalva (236548), John Williams (32544), Zhu, Yuwei, Claudio F Lanata, Hector Verastegui (534417), Kathryn M Edwards, Andrew Wu (90389), Edwards, Kathryn M, John Williams, Yuwei Zhu (236550), Budge, Philip J, Johnson, Monika, Hartinger, Stella, Ana I. Gil (534420), Lanata, Claudio F, Ana I Gil, Claudio F. Lanata, Edwards, Kathryn M., Philip J. Budge, Griffin, Marie R, Carlos G Grijalva, Andrew Wu, Kathryn M. Edwards, Claudio F. Lanata (454212), Monika Johnson (12861), Budge, Philip J., Griffin Marie R., Grijalva Carlos G., Johnson Monika, Hartinger Stella, Lanata Claudio F., Zhu Yuwei, Verastegui Hector, Budge Philip J., Williams John, Wu Andrew, Edwards Kathryn M., Gil Ana I.   +60 more
core   +2 more sources