Results 61 to 70 of about 1,512,759 (352)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core  

Shared decision making and antibiotic benefit-harm conversations: an observational study of consultations between general practitioners and patients with acute respiratory infections [PDF]

, 2018
Background Little research has examined whether shared decision making (SDM) occurs in consultations for acute respiratory infections (ARIs), including what, and how, antibiotic benefits and harms are discussed.
Bakhit, Mina, Del Mar, Chris, Gibson, Elizabeth, Hoffmann, Tammy   +3 more
core   +4 more sources

Quality Of Care For Acute Respiratory Infections During Direct-To-Consumer Telemedicine Visits For Adults.

Health Affairs, 2018
In direct-to-consumer telemedicine, physicians treat patients through real-time audiovisual conferencing for common conditions such as acute respiratory infections.
Zhuo Shi, A. Mehrotra, C. Gidengil, Sabrina J. Poon, L. Uscher-Pines, Kristin N. Ray   +5 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Optimization of the therapy of ARVI and influenza in outpatient practice

Лечащий Врач
Background. Acute respiratory viral infections are a pathology that most often occurs in outpatient therapeutic practice (about 40 million cases per year). The term acute respiratory viral infection is a collective concept and denotes a group of diseases
D. S. Sukhanov, V. V. Basina, Yu. S. Alekseeva, E. V. Timofeev   +3 more
doaj   +1 more source

Ketoprofen lysine salt as an alternative method of treatment of acute respiratory infections in children

Вопросы современной педиатрии, 2013
Acute respiratory infections are the most common disorders among children. Fever is a frequent and one of the main symptoms of acute respiratory infections. Prompt therapy contributes to more rapid recovery and prevents development of complications.
T. A. Kruchkova
doaj   +1 more source

Prevalence of respiratory pathogens in nasal swabs from horses with acute respiratory disease in Belgium [PDF]

, 2016
Contagious respiratory infections are an important cause of respiratory disease in horses, resulting in impaired pulmonary function, poor performance and sometimes severe illness.
Amory, H, Broux, Barbara, Deprez, Piet, Frippiat, T, Gasthuys, Frank, Gryspeerdt, Annick, Legrand, L, Pardon, Bart   +7 more
core  

Delayed antibiotic prescriptions for respiratory infections [PDF]

, 2017
Background: Concerns exist regarding antibiotic prescribing for respiratory tract infections (RTIs) owing to adverse reactions, cost, and antibacterial resistance. One proposed strategy to reduce antibiotic prescribing is to provide prescriptions, but to
Del Mar, Chris B, Dooley, Liz, Farley, Rebecca, Foxlee, Ruth, Spurling, Geoffrey K P   +4 more
core   +1 more source

Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]

, 2020
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul, De Herdt, Veerle, Garrez, Ieme, Hemelsoet, Dimitri, Laureys, Guy, Raedt, Robrecht, Vonck, Kristl   +6 more
core   +2 more sources