Results 71 to 80 of about 486,348 (304)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Viral etiologies of acute respiratory tract infections among hospitalized children – A comparison between single and multiple viral infections

Journal of Microbiology, Immunology and Infection, 2019
Background: Acute respiratory tract infections are commonly caused by viruses in children. The differences in clinical data and outcome between single and multiple viral infections in hospitalized children were analyzed.
Chun-Yu Yen, Wan-Tai Wu, Chia-Yuan Chang, Ying-Chi Wong, Chou-Cheng Lai, Yu-Jiun Chan, Keh-Gong Wu, Miao-Chiu Hung   +7 more
doaj   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core  

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet, Amberg, Sean M, Chen, Yen Ting, Craik, Charles S, Goetz, David H, Hansell, Elizabeth, Lu, Kai, McKerrow, James, Roush, William R, Simmons, Graham, Zhou, Yanchen   +10 more
core   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study)

Annals of Intensive Care, 2020
Introduction Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the epidemiology of respiratory viruses in this population.
Alexandre Elabbadi, Jérémie Pichon, Benoit Visseaux, Aurélie Schnuriger, Lila Bouadma, Quentin Philippot, Juliette Patrier, Vincent Labbé, Stéphane Ruckly, Muriel Fartoukh, Jean-François Timsit, Guillaume Voiriot   +11 more
doaj   +1 more source

Viral etiology and the impact of co-detection in young children presenting with influenza-like illness [PDF]

, 2016
Background: Children with acute respiratory tract infection (ARTI) frequently exhibit viral-viral codetection, yet its clinical significance remains contentious.
Blyth, Christopher C., Conway, Nicholas, de Klerk, Nicholas, Effler, Paul V., Keil, Anthony D., Levy, Avram, Lim, Faye J., Moore, Hannah C., Richmond, Peter C., Smith, David W., Tempone, Simone, Wake, Zoe V.   +11 more
core   +2 more sources

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Associations between adjustment disorder and hospital-based infections in the Danish population. [PDF]

, 2020
OBJECTIVE:There is some evidence that posttraumatic stress disorder (PTSD) is associated with increased risk of infections, and it is unknown whether adjustment disorder is as well.
Farkas, Dóra Körmendiné, Galea, Sandro, Gradus, Jaimie L, Jiang, Tammy, Lash, Timothy L, Smith, Meghan L, Sumner, Jennifer A, Sørensen, Henrik Toft   +7 more
core  

Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs [PDF]

, 1999
Detection of respiratory viruses by realtime multiplexed PCR (M-PCR) and of RSV by M-PCR and immunofluorescence(IF) was evaluated using specimens collected by nasopharyngeal flocked swab(NFS) and nasal wash(NW).
Munywoki, Patrick, Hamid, Fauzat, Mutunga, Martin, Welch, Steve, Cane, Patricia, Nokes, D. James   +5 more
core   +2 more sources