Results 81 to 90 of about 442,439 (345)

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Respiratory syncytial virus outbreak in a long-term care facility detected using reverse transcriptase polymerase chain reaction: an argument for real-time detection methods. [PDF]

, 2009
ObjectivesTo report an outbreak of respiratory synctyial virus (RSV) in a long-term care facility (LTCF) during ongoing routine respiratory illness surveillance.DesignRapid antigen testing, viral culture, direct fluorescent antibody (DFA) testing, and ...
Caram, L Brett, Chen, Jodi, Hillyard, David R, Petti, Cathy A, Polage, Christopher R, Schmader, Kenneth, She, Rosemary, Taggart, E William, Twersky, Jack, Woods, Christopher W   +9 more
core  

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora, Buttinelli, Gabriele, Campagna, Ilaria, Carsetti, R., Concato, C., DI MATTIA, Greta, Fedele, Giorgio, Ferretti, Beatrice, Frassanito, Antonella, Gesualdo, Francesco, Gonfiantini, Michaela Veronika, Marcellini, Valentina, Midulla, Fabio, Nenna, Raffaella, Nicolai, Ambra, Pandolfi, Elisabetta, Pierangeli, Alessandra, Russo, Luisa, Schiavoni, I., Stefanelli, P., Tozzi, A. E., Vennarucci, Valentina Spuri, Villani, Alberto   +22 more
core   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Effects of Coronavirus Disease 2019 on Prevalence of Acute Respiratory Viruses: Changes during the Pandemic

Journal of Global Infectious Diseases
Introduction: The coronavirus disease 2019 (COVID-19) pandemic may have influenced the prevalence and seasonality of acute respiratory viral infections. The aim of the study was to investigate the prevalence of all viruses causing acute viral respiratory
Yonghee Lee, Tae Su Jang, Jae Kyung Kim
doaj   +1 more source

Kagocel in the therapy of influenza and acute respiratory viral infections: Data analysis and systematization from the results of preclinical and clinical trials [PDF]

Терапевтический архив, 2017
The article provides the summarized data of clinical trials evaluating the efficacy and safety of kagocel used to prevent and treat influenza and acute respiratory viral infections of different etiologies. The results of numerous preclinical and clinical
T V Sologub, V V Tsvetkov
doaj   +1 more source

Clinical features and viral etiology of acute respiratory infection in an outpatient fever clinic during COVID‐19 pandemic in a tertiary hospital in Nanjing, China [PDF]

, 2022
Yu Geng, Yingying Hao, Xiao‐Ming Xu, Rui Huang, Fei He, Jun Ni, Jie Zhan, Yuxin Chen, FengHua Hu, Chao Wu   +9 more
openalex   +1 more source

Acute Otitis Media and Other Complications of Viral Respiratory Infection [PDF]

Pediatrics, 2016
BACKGROUND: Viral upper and lower respiratory tract infections (URI, LRI) are common in infants. We determined the prevalence of viral URI and its complications, including acute otitis media (AOM) and LRI, and assessed the effect of bacterial-viral interactions, and genetic and environmental risks on AOM development.
Tasnee, Chonmaitree, Rocio, Trujillo, Kristofer, Jennings, Pedro, Alvarez-Fernandez, Janak A, Patel, Michael J, Loeffelholz, Johanna, Nokso-Koivisto, Reuben, Matalon, Richard B, Pyles, Aaron L, Miller, David P, McCormick   +10 more
openaire   +2 more sources

Transparent UV‐Curable Self‐Sanitizing Coatings Applicable to Diverse Surfaces and High‐Touch Screens to Mitigate Deadly Pathogen Transmission

Advanced Functional Materials, EarlyView.
Development of a transparent, self‐sanitizing antimicrobial coating technology applicable to a wide range of materials and surfaces‐including touchscreens, transparent substrates, and metal, plastic, and glass‐regardless of pathogen type. The spray‐coated, UV‐cross‐linked imidazole‐based quaternary ammonium chloride materials provide broad‐spectrum ...
Surjith Kumaran, Sumin Han, Euna Oh, Chunghee Jo, Hyerin Shin, Dae‐Hong Ko, Hyo‐Jick Choi   +6 more
wiley   +1 more source