Results 151 to 160 of about 27,818 (259)

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Acute retinal necrosis during the systemic use of Janus kinase inhibitor. [PDF]

open access: yesInt J Retina Vitreous
Watanabe D   +12 more
europepmc   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang   +12 more
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Acute retinal necrosis associated with dimethyl fumarate. [PDF]

open access: yesMult Scler
Paisey C, Curtin K, Epps SJ, Rice CM.
europepmc   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Acute retinal necrosis and HIV

open access: yesIndian Journal of Ophthalmology, 2002
Mukerji Nitin   +2 more
doaj  

Long-term outcomes of combination systemic and intravitreal antiviral therapy in the management of acute retinal necrosis. [PDF]

open access: yesJ Ophthalmic Inflamm Infect
Wade AR   +6 more
europepmc   +1 more source

Prevalence and Severity of Coronary Artery Calcification Assessed by Low‐Dose Computed Tomography in Individuals With Type 2 Diabetes With and Without Diabetic Foot: A Cross‐Sectional Study

open access: yesJournal of Diabetes, Volume 18, Issue 6, June 2026.
Diabetic foot is independently associated with the presence and severity of coronary artery calcification in patients with type 2 diabetes. Patients developing diabetic foot or with impaired renal function may warrant enhanced cardiovascular risk assessment and screening for silent coronary artery disease.
Feiyan Shi   +11 more
wiley   +1 more source

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