Results 131 to 140 of about 27,818 (259)

Antiviral treatment for acute retinal necrosis

La necrosis retiniana aguda es un síndrome inflamatorio intraocular progresivo caracterizado por una retinitis necrotizante difusa que puede conducir a un mal resultado visual, principalmente por desprendimiento de retina.
Gupta, V., Cifuentes-González, C., Ridwan, AS., Mahendradas, P., Agrawal R., Biswas, J., Pavesio, C., Edwar, L., Kempen, JH., Putera, I., Susiyanti, M., Chee, SP., Rojas-Carabali, W., Aziza, Y., Dewi, M., Sitompul, R., de-la-Torre, Alejandra, La Distia Nora R.   +17 more
core   +1 more source

Acute retinal necrosis in an acute leukemia pediatric patient Necrosis retinal aguda en un paciente pediátrico con leucemia aguda [PDF]

, 2007
Acute retinal necrosis (ARN) is a serious condition that can impair vision. It mostly occurs in adult patients, especially those severely immunocompromised, in association with a reactivation of a herpes virus infection.
Concha V., Emma, Torres Torretti, Juan Pablo, López G., Juan P., Cofré G., José   +3 more
core  

STING activates ZBP1-mediated PANoptosis to defend against HSV-1 retinal infection

Journal of Neuroinflammation
Herpes simplex virus type 1 (HSV-1) is the most common cause of infectious blindness and is a major cause of acute retinal necrosis (ARN), a severe condition marked by rapid necrosis of the retina.
Wei Liu, Haifeng Cui, Li Wang, Xiangyu Ge, Xingfei Zhu, Xingmiao Liang, Ziqing Chen, Yuwen Gan, Le Shi, Xuebin Hu, Xiaohu Ding, Zhengjie Xu, Xiaoling Liang, Lili Gong   +13 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, Volume 13, Issue 35, 24 June 2026.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Viral Pathogens Threatening Cage‐Cultured Nile Tilapia in Lake Victoria: Epidemiology, Emerging Risks and Integrated Health Management Strategies

Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT The rapid expansion of cage culture for Nile tilapia (Oreochromis niloticus) in Lake Victoria is central to food security and profitable development in East Africa. Nevertheless, viral conditions affect the sustainability of this sector, with significant imbalances in livelihood, trade and aquaculture adaptability.
Richard S. Komba, Chacha J. Mwita
wiley   +1 more source

Double‐Stranded DNA Sensing cGAS‐STING Immune Signaling in a Rat Co‐Culture Model of the Blood–Brain Barrier

Cell Biochemistry and Function, Volume 44, Issue 6, June 2026.
ABSTRACT Double‐stranded DNA coming from, for example, viruses, bacteria, or apoptotic cells is recognized by the cGAS‐STING signaling pathway comprising the cyclic GMP‐AMP synthase (cGAS) and the stimulator of interferon genes (STING) receptors. The pathway induces type I interferon response and activates transcription of interferon‐stimulated genes ...
András Harazin, Line S. Reinert, Parvez Alam, Lea Hoy, Annemette Boe Marnow, Janni Nielsen, Anna Lorentzen, Daniel E. Otzen, Søren R. Paludan, Morten S. Nielsen   +9 more
wiley   +1 more source

Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF‐κB and STAT3 pathways in osteosarcoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz, Meltem Alper, Feyza Nur Sav, Tuğşen Aydemir, Feray Köçkar   +4 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

Lysine lactylation‐mediated post‐translational modification: Molecular mechanisms and therapeutic target exploration in tumour drug resistance

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li, Yan Shang, Haojie Wu, Shenglong Yang, Maiqun Zuo, Hailong Zhao   +5 more
wiley   +1 more source

Acute Retinal Necrosis in an Infant With Corneal and Macular Scarring. [PDF]

J Vitreoretin Dis
Zaidi Z, Hansen C, Dogan S, Wang AL.
europepmc   +1 more source