Results 111 to 120 of about 388 (169)
Glucose Transporter 1 in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
Nucleotide Metabolism in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, Volume 7, Issue 4, August 2026.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods +4 more
wiley +1 more source
Allergy, Volume 81, Issue 8, Page 2775-2791, August 2026.ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Infection control in the brain and the eye
Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Cell Proliferation, Volume 59, Issue 8, August 2026.Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.ABSTRACT Background Hyaluronic acid (HA) and calcium hydroxylapatite (CaHA) fillers are among the most widely used injectable materials in aesthetic medicine. Although both exhibit favorable safety profiles, concomitant with increasing use comes a broader spectrum of reported complications, ranging from mild, self‐limited reactions to rare but ...
Natalia Sukmanskaya +2 more
wiley +1 more source
Progressive subretinal fibrosis following acute retinal necrosis
Indian Journal of Ophthalmology. Case ReportsBhuvaneshwaran Vedapuri Eswaran +1 more
doaj +1 more source