Results 101 to 110 of about 28,413 (223)
Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy +2 more
wiley +1 more source
Altitudinal Visual Field Defect as the Presenting Sign of a Brain Tumor: A Case Report
ABSTRACT Brain tumors present with symptoms depending on their type, location, and stage. Most cause visual field defects respecting vertical meridians. Compressive optic neuropathy may produce altitudinal defects, mimicking ischemic optic neuropathy.
Farid Shekarchian +2 more
wiley +1 more source
Differential expression of TKS4 isoforms and their role in cellular processes in breast cancer
TKS4 isoforms are differentially expressed across human cell lines. TKS4L interacts with six novel SRC homology 3‐containing proteins, whereas no interactions were detected for TKS4b. SRC‐mediated phosphorylation promotes interactions of TKS4 with SH2 domains.
Serhii Kropyvko +10 more
wiley +1 more source
Ganoderic Acid A Ameliorates Pentylenetetrazol‐Induced Epilepsy in Mice via Activating KCNQ2
GA‐A binds and activates KCNQ2, thereby reducing epileptic‐like EEG discharges, the loss and apoptosis of hippocampal neurons, and improving anxiety and depression‐like behavioral changes. In addition, GA‐A inhibits neuroinflammation and alleviates oxidative stress independent of activating KCNQ2.
Yang Yao +5 more
wiley +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source
The regulation of stem cell fate and its application in neural regeneration
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Exogenous melatonin, especially when given at night, provides strong neuroprotective benefits by influencing circadian serum melatonin levels. It inhibits PI3K‐dependent inflammatory signaling and encourages the nuclear translocation of NRF2, along with activation of the NRF2/HO‐1 antioxidant pathway.
Alaa Gamal Ahmad +4 more
wiley +1 more source
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source

