Results 61 to 70 of about 28,413 (223)

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Bilateral acute retinal necrosis associated with bilateral uveal effusion in an immunocompetent patient: A challenging association

Indian Journal of Ophthalmology, 2018
Bilateral uveal effusion syndrome associated with bilateral acute retinal necrosis is a diagnostic and therapeutic challenge. A 52 year old man presented with bilateral angle closure with choroidal detachment.
S Bala Murugan, Girish Bharat Velis, Manavi D Sindal   +2 more
doaj   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Acute Retinal Necrosis Associated with Herpes Simplex Virus Type II Infection – Case Report

Okulistyka
Introduction Acute retinal necrosis is a rare, severe retinitis that may lead to loss of vision. This condition is caused mainly by the Herpesviridae. It can affect both immunocompromised and immunocompetent patients of all ages.
Paulina Dymek, Alicja Pawlicka, Natalie Papachristoforou, Maciej Kozak, Urszula Szpakowicz, Katarzyna Kozicka, Ilona Pawlicka   +6 more
doaj   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Advances in deep‐tissue fluorescence imaging through optical clearing: A review

VIEW, EarlyView.
Optical clearing refers to techniques that are used to improve the optical transparency of biological tissues. Optical clearing enables imaging of deeper lying tissues as well as 3D volumetric imaging of whole organs. This review examines reports on the integration of optical clearing with advanced fluorescence imaging techniques, with particular ...
Alaka Pramod, Sanoop Pavithran M, Valery V. Tuchin, Santhosh Chidangil, C. S. Suchand Sandeep   +4 more
wiley   +1 more source

Bilateral acute retinal necrosis with choroidal detachment

Indian Journal of Ophthalmology. Case Reports
A 42-year-old man with history of topiramate intake presented with sudden diminution of vision. He was diagnosed with bilateral panuveitis with retinitis and serous choroidal detachment, with ultrasound biomicroscopy revealing ciliary body effusion ...
Akanksha Sharma, Uday Tekchandani, Swechya Neupane, Ramandeep Singh   +3 more
doaj   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Bilateral acute retinal necrosis-A case report

Indian Journal of Ophthalmology, 1992
A 42 year old man presented with acute bilateral uveitis and necrotizing retinitis. Systemic investigations including test for AIDS and CMV retinitis were negative.
Prasad Palimar, Upadhyaya N
doaj  

Acute retinal necrosis secondary to Varicella Zoster Virus

IDCases, 2019
A 54 year old female presented to the ophthalmology clinic with pain and decreased vision in her left eye. No past medical history other than primary varicella zoster infection, in her childhood.
Archana Vasudevan, Christian Rojas-Moreno, Tushar Tarun   +2 more
doaj   +1 more source