Results 101 to 110 of about 35,095 (251)

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang   +5 more
wiley   +1 more source

Rheumatic heart disease: how many interventions and complications can a patient overcome?

open access: yesRomanian Journal of Cardiology
Rheumatic heart disease (RHD) is a serious, long-term consequence of acute rheumatic fever that is characterized by progressive evolution over the years.
Niţă Bianca Adriana   +4 more
doaj   +1 more source

Vector-borne threats: Sustainable approaches to their diagnosis and treatment [PDF]

open access: yesarXiv
Arbovirus is a vital, life-threatening disease worldwide and continues to be a significant problem while the world is dealing with the major coronavirus (COVID-19) pandemic. Vectors, mostly mosquitoes and ticks, transmit this disease. Dengue fever, chikungunya, and Zika viruses are the major threats because of their high incidence, public health burden,
arxiv  

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

open access: yesBritish Journal of Pharmacology, EarlyView.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding   +5 more
wiley   +1 more source

Improving Delivery of Secondary Prophylaxis for Rheumatic Heart Disease in a High‐Burden Setting: Outcome of a Stepped‐Wedge, Community, Randomized Trial

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Health system strengthening is needed to improve delivery of secondary prophylaxis against rheumatic heart disease. Methods and Results We undertook a stepped‐wedge, randomized trial in northern Australia.
Anna P. Ralph   +9 more
doaj   +1 more source

Dengue Fever in Perspective of Clustering Algorithms [PDF]

open access: yesarXiv, 2015
Dengue fever is a disease which is transmitted and caused by Aedes Aegypti mosquitos. Dengue has become a serious health issue in all over the world especially in those countries who are situated in tropical or subtropical regions because rain is an important factor for growth and increase in the population of dengue transmitting mosquitos.
arxiv  

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