Results 51 to 60 of about 52,052 (262)

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Acute rheumatic fever [PDF]

, 2016
Akut romatizmal ateş grup A streptokok farenjitinin çoklu organ sistemini etkileyen enflamatuvar bir bağ dokusu hastalığıdır. En sık 5-15 yaş arasında görülmekle birlikte; 5 yaş altındaki olgular, toplam hasta sayısının %3-5'ini oluşturmaktadır ...
Köksal, Ali Osman, Soylu, Asiye Gültekin, Özdemir, Osman   +2 more
core  

Sydenham's chorea in a 16‐year‐old female from Bhutan: A case report

Clinical Case Reports
Key Clinical Message Rheumatic heart disease is a preventable disease. Patients may not present with a typical history of sore throat and polyarthritis but may present with Sydenham's chorea. We should not rely completely on clinical findings to rule out
Tshering Penjor, Thinley Dorji, Sangay Wangchuk   +2 more
doaj   +1 more source

Guidelines for the secondary prevention of rheumatic heart disease Endorsed by Saudi Pediatric Infectious Diseases Society (SPIDS)

International Journal of Pediatrics & Adolescent Medicine, 2017
Rheumatic fever is a rare yet serious condition develop as a consequence of throat infection caused by Streptococcus pyogenes. It is the leading cause for rheumatic heart disease. Rheumatic heart disease is a worldwide public health concern.
Abdulrazaq Al-Jazairi, Razan Al-Jaser, Zohair Al-Halees, Mai Shahid, Mansour Al-Jufan, Sulaiman Al-Mayouf, Abdulrahman Al-Rajhi, Sami Al-Hajjar   +7 more
doaj   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

The Treatment of Acute Rheumatic Fever [PDF]

, 2020
Hydroxychloroquine (HCQ) suppresses an interleukin-1β-granulocyte-macrophage colony-stimulating factor cytokine axis, reported to be dysregulated in peripheral blood mononuclear cells of acute rheumatic fever patients ex vivo.
Rachel Webb, William John Martin, Nicole J. Moreland, Webb, Rachel, Anthony Concannon, Malcolm, J, Martin, WJ, Sarka Davidakova, Moreland, Nicole, Davidkova, S, Wilson, NJ, Nigel J. Wilson, John Malcolm, Concannon, A   +13 more
core   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Acute rheumatic fever in Tunisia. Serotypes of group A streptococci associated with rheumatic fever. [PDF]

, 1997
International audienceRheumatic fever (RF) is a serious health threat in our country. The annual incidence of cases of acute rheumatic fever (ARF) in 1990 was 30 per 100,000 school-aged children, the prevalence of rheumatic heart diseases (RHD) was 3–6 ...
Kechrid, P, Kharrat, H, Bousnina, S., Kriz, P, Kaplan, E   +4 more
core   +1 more source

Tenascin-C: as a diagnostic biomarker for rheumatic heart disease

Egyptian Pediatric Association Gazette, 2023
Background Rheumatic fever is a long-term inflammatory disease that can happen if group A beta-hemolytic streptococci bacteria are not treated well enough.
Maha M. A. Abo-Hashish, Azza Mohamed Ahmed, Mohammad Ali Hegazi, Naglaa Abdel Rahman Mosaad, Mona Hammed Ibrahim, Nagwan Yehia Abdel Salam   +5 more
doaj   +1 more source