Results 51 to 60 of about 1,869,911 (214)

A Single-center Experience in Children with Acute Rheumatic Fever

Bagcilar Medical Bulletin
Objective: This retrospective study aimed to emphasize the importance of subclinical carditis in children with acute rheumatic fever before the revised 2015 Jones criteria.
Nagehan Bilgeç, Fatih Şap, Tamer Baysal   +2 more
doaj   +1 more source

Assessment of Mothers’ Knowledge and Practices Regarding Care of their Children with Rheumatic Fever [PDF]

Helwan International Journal for Nursing Research and Practice
Rheumatic fever refers to an autoimmune response to an untreated infection of the throat and possibly skin by group A streptococcus bacteria. The study aimed to: assess mothers’ knowledge and practices regarding care of their children with rheumatic ...
Eman elsayed
doaj   +1 more source

Tenascin-C: as a diagnostic biomarker for rheumatic heart disease

Egyptian Pediatric Association Gazette, 2023
Background Rheumatic fever is a long-term inflammatory disease that can happen if group A beta-hemolytic streptococci bacteria are not treated well enough.
Maha M. A. Abo-Hashish, Azza Mohamed Ahmed, Mohammad Ali Hegazi, Naglaa Abdel Rahman Mosaad, Mona Hammed Ibrahim, Nagwan Yehia Abdel Salam   +5 more
doaj   +1 more source

The Treatment of Acute Rheumatic Fever

, 2020
Hydroxychloroquine (HCQ) suppresses an interleukin-1β-granulocyte-macrophage colony-stimulating factor cytokine axis, reported to be dysregulated in peripheral blood mononuclear cells of acute rheumatic fever patients ex vivo.
Rachel Webb, William John Martin, Nicole J. Moreland, Anthony Concannon, Malcolm, J, Martin, WJ, Sarka Davidakova, Davidkova, S, Wilson, NJ, Nigel J. Wilson, John Malcolm, Concannon, A, Moreland, NJ, Webb, RH   +13 more
core   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes

Drugs in R&D
Superficial infections with Streptococcus pyogenes (Strep A), pharyngitis and impetigo can induce acute rheumatic fever, an autoimmune sequela manifesting mostly with arthritis and rheumatic carditis.
Usman Nakakana, Alimamy Serry-Bangura, Bassey Effiom Edem, Pietro Tessitore, Leonardo Di Cesare, Danilo Gomes Moriel, Audino Podda, Iris Sarah De Ryck, Ashwani Kumar Arora   +8 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Echocardiography in acute rheumatic fever and rheumatic heart disease

, 2018
Echocardiography has an important role in the diagnosis of acute rheumatic fever (ARF) and chronic rheumatic heart disease and requires integration of morphological abnormalities with abnormal valvular haemodynamic characteristics.
Ruchika Meel, Ferande Peters, Mohammed R. Essop   +2 more
core   +1 more source

Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature

Italian Journal of Pediatrics, 2012
Background Acquired complete heart block, in pediatric age is mainly the results of direct injury to conduction tissue during cardiac surgery or cardiac catheterisation.
Carano Nicola, Bo Ilaria, Tchana Bertrand, Vecchione Erica, Fantoni Silvia, Agnetti Aldo   +5 more
doaj   +1 more source

Difficulties in the Diagnosis of Acute Rheumatic Fever without Carditis, Karditsiz Akut Romatizmal Ateş Tanısında Zorluklar

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 2020
Introduction: Acute rheumatic fever is a childhood disease that is still important in terms of both morbidity and mortality due to heart valve involvement in adulthood.
Mahmut Keskin
doaj   +1 more source