Results 61 to 70 of about 51,881 (280)

Epidemiology of acute rheumatic fever and rheumatic heart disease

, 2018
This chapter outlines the current best estimates for mortality and morbidity for group A Streptococcus, acute rheumatic fever, and rheumatic heart disease and in particular highlights the disproportionate burden of disease.
Liesl Zühlke
core   +1 more source

Association of Childhood Acute Leukemia With Autoimmune Diseases

International Journal of Cancer, EarlyView.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka, Julia Ventelä, Anssi Auvinen, Olli Lohi, Atte Nikkilä   +4 more
wiley   +1 more source

Low-Dose Interleukin-2 Therapy: A Transformative Approach for the Management of Autoimmune Complications Associated with Streptococcus pyogenes Infections

Proceedings
Acute rheumatic fever is an autoimmune inflammatory reaction to Streptococcus pyogenes infections, leading to progressive heart valve damage and rheumatic heart disease (RHD) [...]
Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Despena Vedis, Harshi Weerakoon, Natkunam Ketheesan, Michael F. Good, Manisha Pandey   +6 more
doaj   +1 more source

Real‐World Usage and Outcomes of Different Siltuximab Dosing Frequency in Idiopathic Multicentric Castleman Disease

American Journal of Hematology, EarlyView.
Yoshito Nishimura, Maria Santiago Estevez, Hakeem Asad, Thomas Habermann, Angela Dispenzieri   +4 more
wiley   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Coréia de Sydenham: estudo clínico-evolutivo de 53 casos. [PDF]

, 1988
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Corrêa Neto, Ylmar
core  

Asprosin as a Potential Link Between Vascular Inflammation and Disease Activity in Behçet's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Serum asprosin levels are significantly elevated in patients with Behçet's disease compared to healthy controls. Asprosin concentrations increase progressively with disease activity and are strongly associated with vascular involvement and uveitis, suggesting a potential role as a biomarker of vascular inflammation and disease severity.
Zeynep Kaya, Mesude Seda Aydogdu, Cihat Ucar, Mehmet Nur Kaya, Sezgin Zontul, Elif Inanc, Servet Yolbas   +6 more
wiley   +1 more source

Increased ischaemia-modified albumin is associated with inflammation in acute rheumatic fever [PDF]

, 2014
Introduction: Ischaemia-modified albumin, a novel biochemical marker for tissue ischaemia, was found to be associated with oxidative stress. The purpose of this study was to assess the role of ischaemia-modified albumin in the diagnosis of acute ...
Baysal, Tamer, Sap, Fatih, Mehmetoglu, Idris, Karatas, Zehra, Alp, Hayrullah   +4 more
core   +1 more source

Treating acute rheumatic fever

BMJ, 2003
So many years, and yet we do not know if steroids should be used Rheumatic fever is a delayed complication of pharyngeal infection with group β haemolytic streptococci. Susceptible individuals develop a diffuse inflammatory disease of the heart, joints, brain, blood vessels, and subcutaneous tissue.
openaire   +3 more sources

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

Journal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan, David J. McCreary, Adriana Nedyalkova, Peter J. Snelling   +3 more
wiley   +1 more source