Results 51 to 60 of about 14,924 (207)

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui, Yukari Okubo, Satomi Kobayashi, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Masatoshi Abe, Bruce Strober, Melinda Gooderham, Wendy Zhang, Junichiro Shimauchi, Masafumi Yaguchi, Takeshi Kimura, Ryuichi Ogawa, Hamid Amouzadeh, Masamoto Murakami   +15 more
wiley   +1 more source

Bacterial adhesion of palatine tonsils epithelial cells in infectious mononucleosis

Acta Medica Leopoliensia, 2021
Aim. To evaluate the features of pharynx tonsils mucous membrane colonization by pathogenic and opportunistic microorganisms using electron microscopic examination of pharynx palatine tonsils epithelium in patients with infectious mononucleosis and acute
A.B. Nadraga, O.D. Lutsyk, Kh.P. Klymenko, O.Ya. Khomyn   +3 more
doaj   +1 more source

Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities. However, in recent years, researchers have mainly paid attention to its anti‐tumor effect and neglected its anti‐inflammatory effect.
Xixi Liu, Chencheng Li, Jing Yang, Weiguang Zhang, Zhongxiao Hu, Xiaoli Zhang, Reaila Jianati, Fang Tian, Xingbin Dai, Zuqiong Xu, Biqing Chen, Xuejun Zhu   +11 more
wiley   +1 more source

Rhinovirus Infects B and CD4 T Lymphocytes in Hypertrophic Tonsils in Children

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Prolonged detection of rhinovirus (RV) in secretions after a typical cold and asymptomatic shedding are frequently reported. Although RV has been detected in human hypertrophic tonsils, its replicative status and host cell range remain unclear.
Ronaldo Martins, Flavia E. de Paula, Talita B. G. Mitchell, Miria F. Criado, Ricardo S. Cardoso, Bruna L. S. Jesus, Italo A. Castro, Murilo Henrique Anzolini Cassiano, Daniela Méria Ramos Rodrigues, Noilson Oliveira, Lucas Carenzi, Fabiana C. Valera, Edwin Tamashiro, Wilma T. Anselmo‐Lima, Eurico Arruda   +14 more
wiley   +1 more source

STREPTOCOCCAL TONSILLITIS IN CHILDREN

Педиатрическая фармакология, 2012
The problem of acute tonsillitis retains its relevance over the past few years. Its most frequent causative agent is the ß-hemolytic streptococcus group A.
M. M. Polunin, L. S. Titarova, T. A. Polunina   +2 more
doaj   +1 more source

Bilateral Chronic Expanding Hematomas of the Gluteus Maximus Presenting With Gluteal Muscle Contracture: A Case Report

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Chronic expanding hematoma is defined as a progressively enlarging soft tissue mass persisting beyond 1 month, typically resulting from prior trauma or surgical procedures. Although the condition is rare, its occurrence within deep musculature—particularly with bilateral involvement of the gluteus maximus—is exceedingly uncommon. No
Xi‐Qing Pan, Jin‐Hui Liu, Jiang‐Li Zhang, Ya‐Ya Zhang, Jian‐Yong Zhang, Lei Shu, Wei Zhao   +6 more
wiley   +1 more source

Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies

International Journal of Cancer, Volume 158, Issue 1, Page 108-119, 1 January 2026.
What's new? While several nongenetic risk factors are linked to testicular germ‐cell tumors (TGCTs), the influence of environmental and hormonal factors remains unclear. This study evaluated the role of postnatal exposures in the etiology of TGCT using data from the ongoing EPSAM case–control investigation in Italy.
Mauro Cioffi, Giovenale Moirano, Elena Isaevska, Valentina Fiano, Massimo Di Maio, Patrizia Lista, Ilaria Depetris, Andrea Zitella, Pietro Quaglino, Lorenzo Richiardi, Maja Popovic   +10 more
wiley   +1 more source

ACUTE TONSILLITIS IN CHILDREN: A PEDIATRICIAN’S PERSPECTIVE

Педиатрическая фармакология, 2014
This article is dedicated to one of the most widespread pathologies in children – acute tonsillitis, which is a daily routine for both otolaryngologists and pediatricians.
A. D. Vetrova
doaj   +1 more source

Tranexamic Acid for Acute Upper Respiratory Tract Infection‐Associated Sore Throat Pain: A Randomized Controlled Trial

Journal of General and Family Medicine, Volume 27, Issue 1, January 2026.
ABSTRACT Background Tranexamic acid (TXA) is sometimes used to relieve sore throat discomfort from acute upper‐respiratory tract infection (URTI), but its clinical effect has not been demonstrated in robust randomized controlled trials. Methods The tranexamic acid for URTI study is a randomized double‐blinded clinical trial that was conducted between ...
Naoto Ishimaru, Toshio Shimokawa, Masataka Ono, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima   +5 more
wiley   +1 more source

Adult tonsillectomy: postoperative pain depends on indications

Brazilian Journal of Otorhinolaryngology
INTRODUCTION: Intense pain is one of the most important postoperative complaints after tonsillectomy. It is often described by patients as comparable to the pain that accompanies an acute tonsillitis.
Olaf Zagólski, Mariusz Gajda, Pawel Strek, Michael John Kozlowski, Artur Gadek, Jerzy Nyzio   +5 more
doaj   +1 more source