Results 1 to 10 of about 403,794 (119)

Antibiotic therapy in viral airway infections (ATHENIAN): study protocol for an open labeled randomized controlled pragmatic trial to evaluate the efficacy and safety of discontinuing antibiotic therapy in adult patients infected with respiratory viruses [PDF]

Trials
Background Reducing inappropriate use of antibiotics is essential to combat antimicrobial resistance. Antibiotics are widely prescribed upon hospital admission for acute respiratory infections, but it remains unknown whether it is safe to discontinue ...
Magrit Jarlsdatter Hovind, Jan Erik Berdal, Jūratė Šaltytė Benth, Olav Dalgard, Magnus Nakrem Lyngbakken   +4 more
doaj   +2 more sources

A Multiwell-Plate Caenorhabditis elegans Assay for Assessing the Therapeutic Potential of Bacteriophages against Clinical Pathogens

Microbiology Spectrum, 2022
In order to establish phage therapy as a standard clinical treatment for bacterial infections, testing of every phage to ensure the suitability and safety of the biological compound is required.
Prasanth Manohar, Belinda Loh, Namasivayam Elangovan, Archana Loganathan, Ramesh Nachimuthu, Sebastian Leptihn   +5 more
doaj   +1 more source

The Emergence of Carbapenem-Resistant Gram-Negative Bacteria in Mizoram, Northeast India

Microbiology Research, 2022
(Background) Numerous reports on carbapenem resistance in different parts of India have been published, yet there are insufficient studies on the prevalence of antibiotic resistance in the northeast region of the country.
Vanlalruati S. C. Ralte, Archana Loganathan, Prasanth Manohar, Christine Vanlalbiakdiki Sailo, Zothan Sanga, Lalremruata Ralte, John Zothanzama, Sebastian Leptihn, Ramesh Nachimuthu, Nachimuthu Senthil Kumar   +9 more
doaj   +1 more source

Antibacterial efficacy of lytic phages against multidrug-resistant Pseudomonas aeruginosa infections in bacteraemia mice models

BMC Microbiology, 2022
Background Pseudomonas aeruginosa is an opportunistic pathogen that can cause a variety of infections in humans, such as burn wound infections and infections of the lungs, the bloodstream and surgical site infections.
Shri Natrajan Arumugam, Prasanth Manohar, Sunilkumar Sukumaran, Sathish Sadagopan, Belinda Loh, Sebastian Leptihn, Ramesh Nachimuthu   +6 more
doaj   +1 more source

Reduction of Duration of Antibiotic Therapy for Suspected Early-Onset Sepsis in Late-Preterm and Term Newborns After Implementation of a Procalcitonin-Guided Algorithm: A Population-Based Study in Central Switzerland

Frontiers in Pediatrics, 2021
Background: Suspected early-onset sepsis (EOS) is the main reason for antibiotic therapy at the start of life. Prolonged antibiotic therapy for culture-negative sepsis is often reported.
Jennifer Zihlmann-Ji, Jennifer Zihlmann-Ji, Christian Braun, Michael Buettcher, Markus Hodel, Dirk Lehnick, Martin Stocker   +6 more
doaj   +1 more source

Cost-effectiveness of routine versus indicated antibiotic therapy in the management of severe wasting in children

Cost Effectiveness and Resource Allocation, 2022
Background In the outpatient management of severe wasting, routine antibiotic therapy is recommended for all children upon admission regardless of whether clinical signs of infection are present.
Sheila Isanaka, Kevin Tang, Fatou Berthé, Rebecca F. Grais, Ankur Pandya   +4 more
doaj   +1 more source

Appropriate antibiotic therapy is a predictor of outcome in patients with Stenotrophomonas maltophilia blood stream infection in the intensive care unit

Journal of Microbiology, Immunology and Infection, 2023
Background/purpose: The study was to assess the relationship between antibiotic therapy and the outcome in intensive care unit (ICU) patients with Stenotrophomonas maltophilia bloodstream infection (BSI).
Jiun-Ji Lai, L. Kristopher Siu, Feng-Yee Chang, Jung-Chung Lin, Ching-Mei Yu, Rui-Xin Wu, Ching-Hsun Wang   +6 more
doaj   +1 more source

Urinary tract infection in children - short versus standard duration antibiotic therapy

Journal of Education, Health and Sport, 2022
Background: Urinary Tract Infection (UTI) is a common infection in children. Prompt diagnosis and appropriate treatment are very important to reduce the morbidity.
Natalia Namroży, Robert Dubel, Aleksandra Czekaj, Kinga Ruszel, Julia Dubel, Konrad Merkisz, Sylwia Nemeczek, Jakub Grzybowski, Karolina Jaskuła, Władysław Orłowski   +9 more
doaj   +1 more source

The therapeutic potential of bacteriophages targeting gram-negative bacteria using Galleria mellonella infection model

BMC Microbiology, 2018
Background Phage therapy is the therapeutic use of bacteriophages to treat highly drug resistant bacterial infections. The current surge in bacteriophage therapy is motivated mainly because of the emergence of antibiotic-resistant bacteria in clinics ...
Prasanth Manohar, Ramesh Nachimuthu, Bruno S. Lopes   +2 more
doaj   +1 more source

Antibiotic associated diarrhea in outpatient pediatric antibiotic therapy

BMC Pediatrics, 2023
Background Antibiotic-associated diarrhea is one of the most frequent side effects of antimicrobial therapy. We assessed the epidemiological data of antibiotic-associated diarrhea in pediatric patients in our region.
Sevgen Tanır Basaranoğlu, Ayşe Karaaslan, Enes Salı, Ergin Çiftçi, Zeynep Gökçe Gayretli Aydın, Bilge Aldemir Kocabaş, Cemil Kaya, Semra Şen Bayturan, Soner Sertan Kara, Dilek Yılmaz Çiftdoğan, Ümmühan Çay, Hacer Gundogdu Aktürk, Melda Çelik, Halil Ozdemir, Ayper Somer, Tijen Diri, Ahmet Sami Yazar, Murat Sütçü, Hasan Tezer, Eda Karadag Oncel, Manolya Kara, Solmaz Çelebi, Aslınur Özkaya Parlakay, Sabahat Karakaşlılar, Emin Sami Arısoy, Gönül Tanır, Tuğçe Tural Kara, İlker Devrim, Tuğba Erat, Kübra Aykaç, Özge Kaba, Şirin Güven, Edanur Yeşil, Ayşe Tekin Yılmaz, Sevgi Yaşar Durmuş, İlknur Çağlar, Fatih Günay, Metehan Özen, Ener Çağrı Dinleyici, Ateş Kara   +39 more
doaj   +1 more source