Results 31 to 40 of about 3,260,507 (313)

Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature

open access: yes, 2019
This report describes the case of an individual who was clinically diagnosed with Lyme borreliosis and initially responded to standard antibiotic therapy.
Ross Murtagh   +2 more
core   +1 more source

The Etiology, Antibiotic Therapy and Outcomes of Bacteremic Skin and Soft-Tissue Infections in Onco-HematologicalPatients. Antibiotics (Basel).  [PDF]

open access: yes, 2023
Objectives: to assess the current epidemiology, antibiotic therapy and outcomes of oncohematological patients with bacteremic skin and soft-tissue infections (SSTIs), and to identify the risk factors for Gram-negative bacilli (GNB) infection and for ...
Paula Pons-Oltra   +27 more
core   +1 more source

The impact of healthcare-associated infection on mortality: failure in clinical recognition is related with inadequate antibiotic therapy. [PDF]

open access: yesPLoS ONE, 2013
PURPOSE: To understand if clinicians can tell apart patients with healthcare-associated infections (HCAI) from those with community-acquired infections (CAI) and to determine the impact of HCAI in the adequacy of initial antibiotic therapy and hospital ...
Teresa Cardoso   +4 more
doaj   +1 more source

Rapid molecular testing is associated with decreased broad-spectrum antibiotic use among patients with streptococcal bloodstream infections

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
We investigated the impact of rapid diagnostic testing with real-time stewardship intervention on patients with Streptococcal bacteremia. Compared to pre-intervention, patients in the post-intervention group received more rapid antibiotic de-escalation ...
Tyler Tate   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Avoiding pitfalls in antibiotic therapy: the antibiotic stewardship approach

open access: yesMagna Scientia UCEVA, 2022
The aim of this reflection is to determine the effectiveness and safety of ABS interventions. A strong correlation between antibiotic overuse and the growing worldwide resistance, but also with individual side effects is well established and should open
Markus H. Huppertz-Thyssen   +1 more
doaj   +1 more source

pFAR plasmids: New Eukaryotic Expression Vectors for Gene Therapy, devoid of Antibiotic Resistance Markers [PDF]

open access: yes, 2008
Efficient production of eukaryotic expression vectors requires the selection of plasmid-containing bacteria. To avoid the risk of dissemination of antibiotic resistance markers, we developed a new system to produce a family of plasmids Free of Antibiotic
Corinne Marie   +5 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Ineffectiveness of procalcitonin-guided antibiotic therapy in severely critically ill patients: A meta-analysis

open access: yesInternational Journal of Infectious Diseases, 2019
Background: Optimizing antibiotic therapy has an important impact on the management of critically ill patients. Procalcitonin (PCT) is considered to be of possible use in the guidance of antibiotic stewardship; however, its efficacy remains controversial.
Fei Peng   +5 more
doaj   +1 more source

Antibiotic dose and duration of therapy.

open access: yes, 2022
Antibiotic dose and duration of therapy.
Jessica K. Ortwine (7418151)   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy