Results 51 to 60 of about 3,260,507 (313)

Duration of antibiotic therapy.

open access: yes, 2019
Duration of antibiotic therapy.
Sittiga Hassan-Reshat (6707846)   +2 more
core   +1 more source

What Is the Most Effective Empirical Antibiotic Treatment for Early, Delayed, and Late Fracture-Related Infections? [PDF]

open access: yes, 2022
Antibiotic treatment strategies for fracture-related infections (FRI) are often extrapolated from periprosthetic joint infections (PJI), although, in contrast to PJI, detailed analysis of pathogens and their antibiotic resistance is missing.
Hitzenbichler, Florian   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identifying targets for antibiotic stewardship interventions through analysis of the antibiotic prescribing process in hospitals - a multicentre observational cohort study

open access: yesAntimicrobial Resistance and Infection Control, 2020
Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for antibiotic stewardship interventions in hospitals through analysis of the antibiotic ...
Jannicke Slettli Wathne   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Empirical use of antibiotics and adjustment of empirical antibiotic therapies in a university hospital: a prospective observational study

open access: yesBMC Infectious Diseases, 2007
Background Several strategies to optimise the use of antibiotics have been developed. Most of these interventions can be classified as educational or restrictive.
Battegay Manuel   +7 more
doaj   +1 more source

Frontline antibiotic therapy [PDF]

open access: yesClinical Medicine, 2013
The need to use front-line antibiotics wisely has never been greater. Antibiotic resistance and multi-drug resistant infection, driven by antibiotic use, remain major public health and professional concerns. To overcome these infection problems, use of older antibiotics active against multi drug-resistant pathogens is increasing - for example, colistin,
MacGowan, Alasdair P   +1 more
openaire   +3 more sources

Antibiotic prescribing on two medical wards at St Luke’s Hospital : what scope for improvement? [PDF]

open access: yes, 1996
Antibiotics are frequently prescribed drugs and form a significant part of the hospital budget. The literature suggests that prescribing is not without problems and may need constant review. We have no data relating to our hospital.
Fenech, Frederick F.   +3 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The guidelines on antibiotic application in gynaecological oncology [PDF]

open access: yesArchive of Oncology, 2005
Standardized and effective antibiotic therapy regimes in gynecology need to be based on the protocols prescribed by acknowledged specialists. Antibiotic therapy can have either prophylactic or therapeutic purposes.
Mladenović-Segedi Ljiljana   +4 more
doaj   +1 more source

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